Humanized scFv Molecule Specific to an Extracellular Epitope of P2X4R as Therapy for Chronic Pain Management

Chronic pain affects a significant portion of the population, with fewer than 30% achieving adequate relief from existing treatments. This study describes the humanization methodology and characterization of an effective non-opioid single-chain fragment variable (scFv) biologic that reverses pain-re...

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Bibliographic Details
Main Authors: Adinarayana Kunamneni, Karin N. Westlund
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/14/13/953
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