Incidental Finding of Goblet Cell Adenocarcinoma Post Appendectomy: A Rare Case Report
Introduction: One of the most frequent etiologies of an acute abdomen is appendicitis, which ranks as one of the primary reasons for surgical emergencies globally. Goblet cell adenocarcinoma (GCA) of the appendix, is hallmarked for displaying both endocrine and exocrine traits, presenting with symp...
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Knowledge E
2025-06-01
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| Series: | Dubai Medical Journal |
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| author | Fathima Hana Mohamed Naushad Shameema Alam Aliya Ishaq |
| author_facet | Fathima Hana Mohamed Naushad Shameema Alam Aliya Ishaq |
| author_sort | Fathima Hana Mohamed Naushad |
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Introduction: One of the most frequent etiologies of an acute abdomen is appendicitis, which ranks as one of the primary reasons for surgical emergencies globally. Goblet cell adenocarcinoma (GCA) of the appendix, is hallmarked for displaying both endocrine and exocrine traits, presenting with symptoms similar to acute appendicitis, complicating its diagnosis before surgery.
Case Report: We present a case report of a 61-year-old male with a medical history of benign prostatic hyperplasia and depression who presented lower abdominal pain, fever, and diagnosed with acute appendicitis. A laparoscopic appendectomy was performed. Histopathology revealed GCA of the appendix with Ki-67 proliferative index of 10%. After multidisciplinary team (MDT) discussion and further evaluation, he underwent a right colectomy and hyperthermia intraperitoneal chemotherapy (HIPEC).
Conclusion: Goblet cell tumors are rare and often not readily recognized. A multidisciplinary approach including a team of oncologists, pathologists, radiologists, and general surgeons is essential for the intricacy of diagnosis and therapy. Patients undergoing appendectomy due to appendicitis need a thorough evaluation of biopsy specimen to exclude malignancy.
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| format | Article |
| id | doaj-art-8d09bc36eaaa484b9a28c7cd6eb3371f |
| institution | Matheson Library |
| issn | 2571-726X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Dubai Medical Journal |
| spelling | doaj-art-8d09bc36eaaa484b9a28c7cd6eb3371f2025-06-30T09:39:35ZengKnowledge EDubai Medical Journal2571-726X2025-06-018210.18502/dmj.v8i2.19004Incidental Finding of Goblet Cell Adenocarcinoma Post Appendectomy: A Rare Case ReportFathima Hana Mohamed Naushad0https://orcid.org/0009-0009-3838-9633Shameema Alam1https://orcid.org/0009-0006-3705-4792Aliya Ishaq2https://orcid.org/0000-0002-0327-7668College of Medicine, Dubai Medical University, DubaiCollege of Medicine, Dubai Medical University, DubaiCollege of Medicine, Dubai Medical University, Dubai Introduction: One of the most frequent etiologies of an acute abdomen is appendicitis, which ranks as one of the primary reasons for surgical emergencies globally. Goblet cell adenocarcinoma (GCA) of the appendix, is hallmarked for displaying both endocrine and exocrine traits, presenting with symptoms similar to acute appendicitis, complicating its diagnosis before surgery. Case Report: We present a case report of a 61-year-old male with a medical history of benign prostatic hyperplasia and depression who presented lower abdominal pain, fever, and diagnosed with acute appendicitis. A laparoscopic appendectomy was performed. Histopathology revealed GCA of the appendix with Ki-67 proliferative index of 10%. After multidisciplinary team (MDT) discussion and further evaluation, he underwent a right colectomy and hyperthermia intraperitoneal chemotherapy (HIPEC). Conclusion: Goblet cell tumors are rare and often not readily recognized. A multidisciplinary approach including a team of oncologists, pathologists, radiologists, and general surgeons is essential for the intricacy of diagnosis and therapy. Patients undergoing appendectomy due to appendicitis need a thorough evaluation of biopsy specimen to exclude malignancy. https://knepublishing.com/index.php/DMJ/article/view/19004acute appendicitisappendectomygoblet cell adenocarcinomagoblet cell carcinoidhemi-colectomy |
| spellingShingle | Fathima Hana Mohamed Naushad Shameema Alam Aliya Ishaq Incidental Finding of Goblet Cell Adenocarcinoma Post Appendectomy: A Rare Case Report Dubai Medical Journal acute appendicitis appendectomy goblet cell adenocarcinoma goblet cell carcinoid hemi-colectomy |
| title | Incidental Finding of Goblet Cell Adenocarcinoma Post Appendectomy: A Rare Case Report |
| title_full | Incidental Finding of Goblet Cell Adenocarcinoma Post Appendectomy: A Rare Case Report |
| title_fullStr | Incidental Finding of Goblet Cell Adenocarcinoma Post Appendectomy: A Rare Case Report |
| title_full_unstemmed | Incidental Finding of Goblet Cell Adenocarcinoma Post Appendectomy: A Rare Case Report |
| title_short | Incidental Finding of Goblet Cell Adenocarcinoma Post Appendectomy: A Rare Case Report |
| title_sort | incidental finding of goblet cell adenocarcinoma post appendectomy a rare case report |
| topic | acute appendicitis appendectomy goblet cell adenocarcinoma goblet cell carcinoid hemi-colectomy |
| url | https://knepublishing.com/index.php/DMJ/article/view/19004 |
| work_keys_str_mv | AT fathimahanamohamednaushad incidentalfindingofgobletcelladenocarcinomapostappendectomyararecasereport AT shameemaalam incidentalfindingofgobletcelladenocarcinomapostappendectomyararecasereport AT aliyaishaq incidentalfindingofgobletcelladenocarcinomapostappendectomyararecasereport |