Comparative Quantitative Proteomic Analysis of High and Low Toxin-Producing <i>Karenia brevis</i> Strains Reveals Differences in Polyketide Synthase Abundance and Redox Status of the Proteome

Comparative Quantitative Proteomic Analysis of High and Low Toxin-Producing <i>Karenia brevis</i> Strains Reveals Differences in Polyketide Synthase Abundance and Redox Status of the Proteome

To identify differentially abundant polyketide synthases (PKSs) and to characterize the biochemical consequences of brevetoxin biosynthesis, bottom-up, TMT-based quantitative proteomics and redox proteomics were conducted to compare two strains of the Florida red tide dinoflagellate <i>Karenia...

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Bibliographic Details
Main Authors: Kathleen S. Rein, Ricardo Colon, Carlos R. Romagosa, Nicholas R. Ohnikian, Kirstie T. Francis, Samuel R. Rein
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Marine Drugs
Subjects:
<i>Karenia brevis</i>
proteomics
polyketide synthase
brevetoxin
Online Access:https://www.mdpi.com/1660-3397/23/7/291
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