IN VITRO REPROGRAMMING OF NITRIC OXIDE-SYNTHETIC MECHANISMS FOR M1 AND M2 PHENOTYPES OF MURINE PERITONEAL MACROPHAGES: DEPENDENCE ON DIFFERENT SERUM CONCENTRATIONS

IN VITRO REPROGRAMMING OF NITRIC OXIDE-SYNTHETIC MECHANISMS FOR M1 AND M2 PHENOTYPES OF MURINE PERITONEAL MACROPHAGES: DEPENDENCE ON DIFFERENT SERUM CONCENTRATIONS

Abstract. Macrophages are among key players of inflammatory events, acquiring either pro-inflammatory M1, or anti-inflammatory M2 phenotype, dependent on their microenvironment. Some endogenous macrophagereprogramming factors (MRFs), e.g., TGF-β (an M2-inducing agent), are found in blood serum. This...

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Bibliographic Details
Main Authors: S. V. Kruglov, S. V. Lyamina, T. Yu. Vedenikin, O. A. Borodovizyna, I. A. Suvorova, Sh. L. Shimshelashvili, I. Yu. Malyshev
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2014-07-01
Series:Медицинская иммунология
Subjects:
reprogramming
macrophages
phenotype
nitric oxide
Online Access:https://www.mimmun.ru/mimmun/article/view/310
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