Osteocytes function as biomechanical signaling hubs bridging mechanical stress sensing and systemic adaptation

Osteocytes function as biomechanical signaling hubs bridging mechanical stress sensing and systemic adaptation

Osteocytes, the most abundant bone cells embedded within mineralized matrix, are pivotal regulators of skeletal and systemic homeostasis. Recent advances highlight their mechanotransductive roles via mechanosensors, enabling detection of mechanical stimuli and conversion into biochemical signals to...

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Bibliographic Details
Main Authors: Ma Yuze, Jin Hu, Lv Jun, Xu Cheng, Xin Tianwen, Zhang Junqiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Physiology
Subjects:
osteocyte
crosstalk
mechanotransduction
mechanosensor
endocrine
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1629273/full
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