FAS APOPTOTIC GENE POLYMORPHISM (-670A/G) IS ASSOCIATED WITH CLINICAL PHENOTYPES OF SYSTEMIC SCLEROSIS IN A RUSSIAN POPULATION: A PILOT STUDY
The FAS antigen (Apo-1/CD95) is a key molecule of apoptosis in most cell types, including activated immune cells and fibroblasts. The FAS gene promoter region contains a single-nucleotide polymorphism (-670A/G) associated with a substitution of the nucleotide arginine for guanine, which is associate...
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Main Authors: | M. Yu. Krylov, L. P. Ananyeva, O. A. Koneva, M. N. Starovoitova, E. Yu. Samarkina, O. V. Desinova, O. B. Ovsyannikova, E. N. Aleksandrova, A. A. Novikov, I. A. Guseva |
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Format: | Article |
Language: | Russian |
Published: |
IMA PRESS LLC
2017-03-01
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Series: | Научно-практическая ревматология |
Subjects: | |
Online Access: | https://rsp.mediar-press.net/rsp/article/view/2336 |
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