USP39: a key regulator in malignant tumor progression

USP39: a key regulator in malignant tumor progression

Ubiquitin-specific protease 39 (USP39), a member of the USP family, plays a unique role beyond classical deubiquitination by interacting with target molecules and regulating their pre-mRNA splicing, which enhances its functional specificity compared to other USP family members. Growing evidence high...

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Bibliographic Details
Main Authors: Junyan Li, Jinghua Zhong, Jianming Ye, Yi Xiang, Xiangcai Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
cancer
USP39
pre-mRNA splicing
deubiquitination
malignancy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1556011/full
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