Single-cell RNA sequencing reveals altered immune and stromal landscape in primary and liver metastasis of gastric cancer

Single-cell RNA sequencing reveals altered immune and stromal landscape in primary and liver metastasis of gastric cancer

Background: We aimed to identify stromal cells associated with liver metastasis of gastric cancer (GC). Methods: We downloaded single-cell RNA sequencing (scRNA-seq) datasets for GC tissues and adjacent normal tissues (NT), as well as liver metastases (LM) and healthy liver tissues (HL) from GEO. Ad...

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Bibliographic Details
Main Authors: Bin Zhou, Xiaolin Liu, Huanhuan Hu, Zhipeng Li, Shanliang Zhong
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Biochemistry and Biophysics Reports
Subjects:
Gastric cancer
scRNA-seq
Tumor microenvironment
Cytotoxicity
Angiogenesis
Necroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S240558082500250X
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