THE ROLE OF VASCULAR GROWTH FACTORS IN DIABETIC RETINOPATHY AND MACULAR EDEMA DEVELOPMENT

THE ROLE OF VASCULAR GROWTH FACTORS IN DIABETIC RETINOPATHY AND MACULAR EDEMA DEVELOPMENT

The paper discusses the key role of VEGF and PlGF in the pathogenesis of diabetic retinopathy and macular edema and describes the mechanisms of retinal neoangiogenesis under the influence of these factors. An overview of treatment methods of retinopathy and macular edema is given, with a focus on an...

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Bibliographic Details
Main Authors: A. G. Iskhakova, A. V. Zolotarev, D. A. Viktorov, A. N. Toropovsky, A. G. Nikitin
Format: Article
Language:Russian
Published: Real Time Ltd 2018-10-01
Series:Российский офтальмологический журнал
Subjects:
диабетическая ретинопатия
диабетический макулярный отёк
сахарный диабет
эндотелиальный сосудистый фактор роста (vegf)
плацентарный фактор роста (plgf)
анти-vegf
diabetic retinopathy
diabetic macular edema
diabetes mellitus
endothelial vascular growth factor (vegf)
placenta growth factor (plgf)
Online Access:https://roj.igb.ru/jour/article/view/157
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Summary:The paper discusses the key role of VEGF and PlGF in the pathogenesis of diabetic retinopathy and macular edema and describes the mechanisms of retinal neoangiogenesis under the influence of these factors. An overview of treatment methods of retinopathy and macular edema is given, with a focus on anti-VEGF therapy. Anti-VEGF drugs are listed and compared, taking account of the results of their clinical trials. For citation: Iskhakova A.G., Zolotarev A.V., Viktorov D.A., Toropovsky A.N., Nikitin A.G. The role of vascular growth factors in diabetic retinopathy and macular edema development. Russian ophthalmological journal. 2018; 11 (2): 62-9. doi: 10.21516/2072-0076-2018-11-2-62-69 (In Russian).
ISSN:2072-0076
2587-5760

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