Chondroitin sulfate regulates proliferation of Drosophila intestinal stem cells.
The basement membrane (BM) plays critical roles in stem cell maintenance and activity control. Here we show that chondroitin sulfate (CS), a major component of the Drosophila midgut BM, is required for proper control of intestinal stem cells (ISCs). Loss of Chsy, a critical CS biosynthetic gene, res...
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Main Authors: | Collin Knudsen, Ayano Moriya, Eriko Nakato, Rishi Gulati, Takuya Akiyama, Hiroshi Nakato |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2025-05-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1011686 |
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