Assessing functional suitability of a lyophilized formulation containing designed ankyrin repeat proteins for radionuclide imaging of HER2/neu overexpression in malignant tumors

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Assessing functional suitability of a lyophilized formulation containing designed ankyrin repeat proteins for radionuclide imaging of HER2/neu overexpression in malignant tumors

Aim. To study in vitro and in vivo the functional suitability of 99mTc-labeled lyophilized formulation containing designed ankyrin repeat protein (DARPin) G3-(GGGS)3Cys for radionuclide imaging of HER2/neu overexpression in malignant tumors.Materials and methods. To create a targeted protein, a modi...

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Bibliographic Details
Main Authors:	R. N. Varvashenya, A. A. Prach, E. V. Plotnikov, S. M. Deev, M. V. Belousov, M. S. Larkina, V. I. Chernov
Format:	Article
Language:	English
Published:	Siberian State Medical University (Tomsk) 2024-10-01
Series:	Бюллетень сибирской медицины
Subjects:	malignant tumors her2/neu radionuclide diagnosis darpin g3 oxotechnetium lyophilized formulation
Online Access:	https://bulletin.ssmu.ru/jour/article/view/5733
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