Phospholipid-Rich DC-Vesicles with Preserved Immune Fingerprints: A Stable and Scalable Platform for Precision Immunotherapy

Phospholipid-Rich DC-Vesicles with Preserved Immune Fingerprints: A Stable and Scalable Platform for Precision Immunotherapy

Despite the progress in cancer immunotherapy, therapeutic responses in solid tumors remain suboptimal due to the immunosuppressive nature of the tumor microenvironment (TME), limited immune cell infiltration, and inefficient delivery of immune-activating agents. Dendritic cell-based therapies posses...

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Bibliographic Details
Main Authors: Ramon Gutierrez-Sandoval, Francisco Gutierrez-Castro, Natalia Muñoz-Godoy, Ider Rivadeneira, Adolay Sobarzo, Luis Alarcón, Wilson Dorado, Andy Lagos, Diego Montenegro, Ignacio Muñoz, Rodrigo Aguilera, Jordan Iturra, Francisco Krakowiak, Cristián Peña-Vargas, Andres Toledo
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biomedicines
Subjects:
dendritic cell vesicles
phospholipid-rich vesicles
lyophilization stability
immune fingerprinting
cytokine modulation
proteomic analysis
Online Access:https://www.mdpi.com/2227-9059/13/6/1299
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https://www.mdpi.com/2227-9059/13/6/1299

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