Evidence for alcohol-mediated hemolysis and erythrophagocytosis

Evidence for alcohol-mediated hemolysis and erythrophagocytosis

Alcohol-related liver disease (ALD) is the most common liver disease worldwide; however, its underlying molecular mechanisms remain poorly understood. Here, we identify ethanol-mediated hemolysis and erythrophagocytosis as major contributors to ALD pathogenesis using both in vitro and in vivo models...

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Bibliographic Details
Main Authors: Chaowen Zheng, Siyuan Li, Johannes Mueller, Cheng Chen, Huanran Lyu, Guandou Yuan, Ane Zamalloa, Lissette Adofina, Parthi Srinivasan, Krishna Menon, Nigel Heaton, Stephan Immenschuh, Ines Silva, Vanessa Rausch, Seddik Hammad, Steven Dooley, Shilpa Chokshi, Antonio Riva, Songqing He, Sebastian Mueller
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Redox Biology
Subjects:
Alcohol-related liver disease
Alcoholic hepatitis
Bilirubin
Iron overload
Heme
Hemolysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725002551
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