Peculiarities of Antibody Genesis in the Laboratory Animals Immunized with Anthrax Protective Antigen Preparation, <i>Bacillus anthracis</i> Recombinant or <i>Bacillus anthracis</i> Vaccine Strains

Peculiarities of Antibody Genesis in the Laboratory Animals Immunized with Anthrax Protective Antigen Preparation, <i>Bacillus anthracis</i> Recombinant or <i>Bacillus anthracis</i> Vaccine Strains

Protective antigen, extracted from Bacillus anthracis asporogenic recombinant strain, triggers progression of a high-grade adaptive immunity in vivo. Two-fold immunization of rabbits with the purified protein preparation in a dose of 50 mcg induces production of specific antibodies in titers higher...

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Bibliographic Details
Main Authors: P. Yu. Popova, N. I. Mikshis, A. Yu. Goncharova, T. N. Kashtanova, Yu. A. Popov
Format: Article
Language:Russian
Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2012-04-01
Series:Проблемы особо опасных инфекций
Subjects:
anthrax
protective antigen
vaccines
immunity
antibody genesis
Online Access:https://journal.microbe.ru/jour/article/view/801
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