Correlates of HIV treatment adherence self-efficacy among adolescents and young adults living with HIV in southwestern Uganda.

Adherence to antiretroviral therapy (ART) among adolescents and young adults living with HIV (AYLHIV) in sub-Saharan Africa is sub-optimal compared to younger children and older adults. Adherence self-efficacy is one of the intrapersonal factors most strongly correlated with ART adherence. The role...

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Main Authors: Scholastic Ashaba, Charles Baguma, Patricia Tushemereirwe, Denis Nansera, Samuel Maling, Brian C Zanon, Alexander C Tsai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLOS Global Public Health
Online Access:https://doi.org/10.1371/journal.pgph.0003600
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author Scholastic Ashaba
Charles Baguma
Patricia Tushemereirwe
Denis Nansera
Samuel Maling
Brian C Zanon
Alexander C Tsai
author_facet Scholastic Ashaba
Charles Baguma
Patricia Tushemereirwe
Denis Nansera
Samuel Maling
Brian C Zanon
Alexander C Tsai
author_sort Scholastic Ashaba
collection DOAJ
description Adherence to antiretroviral therapy (ART) among adolescents and young adults living with HIV (AYLHIV) in sub-Saharan Africa is sub-optimal compared to younger children and older adults. Adherence self-efficacy is one of the intrapersonal factors most strongly correlated with ART adherence. The role of adherence self-efficacy in ART adherence among AYLHIV is not well studied in Uganda. We enrolled 300 AYLHIV between October and December 2021 from an HIV clinic in southwestern Uganda. We collected information on adherence self-efficacy, HIV stigma, depression, self-management, and social skills. We used linear regression to estimate the association between adherence self-efficacy and the covariates of interest. At multivariable adjustment self-management (b = 0.29, 95% CI 0.23-0.35, p<0.001) and social skills (b = 0.16, 95% CI 0.08-0.24; p<0.001) were statistically significantly associated with adherence self-efficacy. The findings imply that interventions directed at enhancing self-management and social skills in AYLHIV may increase adherence self-efficacy and, potentially, HIV outcomes among AYLHIV.
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spelling doaj-art-82ea1138c3c1423f9da683e33d4f5f4c2025-07-21T05:47:09ZengPublic Library of Science (PLoS)PLOS Global Public Health2767-33752024-01-0149e000360010.1371/journal.pgph.0003600Correlates of HIV treatment adherence self-efficacy among adolescents and young adults living with HIV in southwestern Uganda.Scholastic AshabaCharles BagumaPatricia TushemereirweDenis NanseraSamuel MalingBrian C ZanonAlexander C TsaiAdherence to antiretroviral therapy (ART) among adolescents and young adults living with HIV (AYLHIV) in sub-Saharan Africa is sub-optimal compared to younger children and older adults. Adherence self-efficacy is one of the intrapersonal factors most strongly correlated with ART adherence. The role of adherence self-efficacy in ART adherence among AYLHIV is not well studied in Uganda. We enrolled 300 AYLHIV between October and December 2021 from an HIV clinic in southwestern Uganda. We collected information on adherence self-efficacy, HIV stigma, depression, self-management, and social skills. We used linear regression to estimate the association between adherence self-efficacy and the covariates of interest. At multivariable adjustment self-management (b = 0.29, 95% CI 0.23-0.35, p<0.001) and social skills (b = 0.16, 95% CI 0.08-0.24; p<0.001) were statistically significantly associated with adherence self-efficacy. The findings imply that interventions directed at enhancing self-management and social skills in AYLHIV may increase adherence self-efficacy and, potentially, HIV outcomes among AYLHIV.https://doi.org/10.1371/journal.pgph.0003600
spellingShingle Scholastic Ashaba
Charles Baguma
Patricia Tushemereirwe
Denis Nansera
Samuel Maling
Brian C Zanon
Alexander C Tsai
Correlates of HIV treatment adherence self-efficacy among adolescents and young adults living with HIV in southwestern Uganda.
PLOS Global Public Health
title Correlates of HIV treatment adherence self-efficacy among adolescents and young adults living with HIV in southwestern Uganda.
title_full Correlates of HIV treatment adherence self-efficacy among adolescents and young adults living with HIV in southwestern Uganda.
title_fullStr Correlates of HIV treatment adherence self-efficacy among adolescents and young adults living with HIV in southwestern Uganda.
title_full_unstemmed Correlates of HIV treatment adherence self-efficacy among adolescents and young adults living with HIV in southwestern Uganda.
title_short Correlates of HIV treatment adherence self-efficacy among adolescents and young adults living with HIV in southwestern Uganda.
title_sort correlates of hiv treatment adherence self efficacy among adolescents and young adults living with hiv in southwestern uganda
url https://doi.org/10.1371/journal.pgph.0003600
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