Metabolically Engineered Extracellular Vesicles Released From a Composite Hydrogel Delivery System Regulate the Microenvironment for Periprosthetic Osteolysis Treatment
ABSTRACT Despite remarkable progress in total joint arthroplasty, aseptic loosening of titanium (Ti) alloy persists as a critical clinical challenge due to the poor wear resistance and biological inertness of such implants. Targeting of inflammatory osteolysis and remodelling of the osseointegration...
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Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2025-06-01
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Series: | Journal of Extracellular Vesicles |
Subjects: | |
Online Access: | https://doi.org/10.1002/jev2.70098 |
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