Bases for the study of the safety of medicines. The spectrum of rare and unexpected ad-verse reactions of bisphosphonates

The paper presents a classification of adverse drug reactions and their characteristics. Bisphophonates (BP) that are have been prescribed for more than 30 years to prevent and treat all forms of osteoporosis (OP) and recognized as first-line drugs for its treatment are used as an example to see the...

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Main Authors: I S Dydykina, P S Dydykina, Yu V Muravyev
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2011-12-01
Series:Современная ревматология
Subjects:
Online Access:https://mrj.ima-press.net/mrj/article/view/391
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author I S Dydykina
P S Dydykina
Yu V Muravyev
author_facet I S Dydykina
P S Dydykina
Yu V Muravyev
author_sort I S Dydykina
collection DOAJ
description The paper presents a classification of adverse drug reactions and their characteristics. Bisphophonates (BP) that are have been prescribed for more than 30 years to prevent and treat all forms of osteoporosis (OP) and recognized as first-line drugs for its treatment are used as an example to see the history of investigating rare and unexpected adverse reactions. The direct correlation between the rare adverse reactions of Ps and their use remains to be proven today. The proposal to reduce the prescriptions of BPs is unfounded. The evidence for the efficacy and safety of BPs in OP has been obtained and confirmed by multiple trials and many years X real practice. Alendronate (fosavance) is the most studied BP now.
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language Russian
publishDate 2011-12-01
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record_format Article
series Современная ревматология
spelling doaj-art-80c6d743e7ff43c5a4cd406d0ed8bf1f2025-08-04T14:00:31ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2011-12-0154798610.14412/1996-7012-2011-7061696Bases for the study of the safety of medicines. The spectrum of rare and unexpected ad-verse reactions of bisphosphonatesI S DydykinaP S DydykinaYu V MuravyevThe paper presents a classification of adverse drug reactions and their characteristics. Bisphophonates (BP) that are have been prescribed for more than 30 years to prevent and treat all forms of osteoporosis (OP) and recognized as first-line drugs for its treatment are used as an example to see the history of investigating rare and unexpected adverse reactions. The direct correlation between the rare adverse reactions of Ps and their use remains to be proven today. The proposal to reduce the prescriptions of BPs is unfounded. The evidence for the efficacy and safety of BPs in OP has been obtained and confirmed by multiple trials and many years X real practice. Alendronate (fosavance) is the most studied BP now.https://mrj.ima-press.net/mrj/article/view/391adverse reactionsbisphosphonates
spellingShingle I S Dydykina
P S Dydykina
Yu V Muravyev
Bases for the study of the safety of medicines. The spectrum of rare and unexpected ad-verse reactions of bisphosphonates
Современная ревматология
adverse reactions
bisphosphonates
title Bases for the study of the safety of medicines. The spectrum of rare and unexpected ad-verse reactions of bisphosphonates
title_full Bases for the study of the safety of medicines. The spectrum of rare and unexpected ad-verse reactions of bisphosphonates
title_fullStr Bases for the study of the safety of medicines. The spectrum of rare and unexpected ad-verse reactions of bisphosphonates
title_full_unstemmed Bases for the study of the safety of medicines. The spectrum of rare and unexpected ad-verse reactions of bisphosphonates
title_short Bases for the study of the safety of medicines. The spectrum of rare and unexpected ad-verse reactions of bisphosphonates
title_sort bases for the study of the safety of medicines the spectrum of rare and unexpected ad verse reactions of bisphosphonates
topic adverse reactions
bisphosphonates
url https://mrj.ima-press.net/mrj/article/view/391
work_keys_str_mv AT isdydykina basesforthestudyofthesafetyofmedicinesthespectrumofrareandunexpectedadversereactionsofbisphosphonates
AT psdydykina basesforthestudyofthesafetyofmedicinesthespectrumofrareandunexpectedadversereactionsofbisphosphonates
AT yuvmuravyev basesforthestudyofthesafetyofmedicinesthespectrumofrareandunexpectedadversereactionsofbisphosphonates