Universal Bacterium-Vectored COVID-19 Vaccine Expressing Early SARS-CoV-2 Conserved Proteins Cross-Protects Against Late Variants in Hamsters

Universal Bacterium-Vectored COVID-19 Vaccine Expressing Early SARS-CoV-2 Conserved Proteins Cross-Protects Against Late Variants in Hamsters

<b>Background/Objectives:</b> Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of Coronavirus Disease 2019 (COVID-19), has rapidly evolved, giving rise to multiple Variants of Concern—including Alpha, Beta, Gamma, Delta, and Omicron—which emerged independ...

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Bibliographic Details
Main Authors: Qingmei Jia, Helle Bielefeldt-Ohmann, Saša Masleša-Galić, Richard A. Bowen, Marcus A. Horwitz
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Vaccines
Subjects:
vaccine
single-vector platform
LVS Δ<i>capB</i> vector
COVID-19
SARS-CoV-2
membrane protein
Online Access:https://www.mdpi.com/2076-393X/13/6/633
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