Gene-regulatory programs that specify age-related differences during thymocyte development

Gene-regulatory programs that specify age-related differences during thymocyte development

Summary: T cell development is fundamental to immune system establishment, but how this development changes with age remains poorly understood. Here, we construct a transcriptional and chromatin accessibility atlas of T cell developmental programs in neonatal and adult mice, revealing the ontogeny o...

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Bibliographic Details
Main Authors: Divya Ganapathi Sankaran, Hongya Zhu, Viviana I. Maymi, Isabel M. Forlastro, Ya Jiang, Nathan Laniewski, Kristin M. Scheible, Brian D. Rudd, Andrew Grimson
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725006746
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