Disparities in Seasonal Influenza Vaccination in Europe

ABSTRACT Background Seasonal influenza remains a major public health challenge in Europe, associated with high morbidity, mortality, and socioeconomic burden. Despite the proven efficacy and cost‐effectiveness of vaccination, coverage rates vary substantially across European countries and population...

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Main Authors: Katinka M. Giezeman‐Smits, Bram Palache, Gerrit A. vanEssen, Miloš Jeseňák, Enrique Castro‐Sánchez, Anna Elisabeth Steinberg, Joris vanVugt
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Immunity, Inflammation and Disease
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Online Access:https://doi.org/10.1002/iid3.70186
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author Katinka M. Giezeman‐Smits
Bram Palache
Gerrit A. vanEssen
Miloš Jeseňák
Enrique Castro‐Sánchez
Anna Elisabeth Steinberg
Joris vanVugt
author_facet Katinka M. Giezeman‐Smits
Bram Palache
Gerrit A. vanEssen
Miloš Jeseňák
Enrique Castro‐Sánchez
Anna Elisabeth Steinberg
Joris vanVugt
author_sort Katinka M. Giezeman‐Smits
collection DOAJ
description ABSTRACT Background Seasonal influenza remains a major public health challenge in Europe, associated with high morbidity, mortality, and socioeconomic burden. Despite the proven efficacy and cost‐effectiveness of vaccination, coverage rates vary substantially across European countries and population groups, often falling short of the World Health Organization's target of 75% for older adults. Objective This narrative review aims to identify and explore disparities in seasonal influenza vaccination coverage across European countries and among different population subgroups. It also seeks to examine the underlying causes of these disparities and propose actionable strategies to improve equity in vaccine uptake. Methods A literature search was conducted using the PubMed database for English‐language articles published within the last 5 years. Keywords included: comorbidity, disparity, Europe, inequality, influenza, knowledge, ethnic disparity, seasonal influenza vaccination, socioeconomic disparity, vaccination coverage, and vaccine hesitancy. Additional references were identified from the retrieved articles. Results Widespread disparities in influenza vaccination were observed across various demographic and professional groups. These included disparities by geographic location, ethnicity, socioeconomic status, sex and gender, age, comorbidities, and occupation—particularly among healthcare professionals. Contributing factors included limited knowledge or education, negative attitudes or behaviors toward vaccination, vaccine hesitancy and fatigue, and restricted access to vaccination services. Structural barriers and institutional trust issues also played key roles. Conclusions Addressing disparities in influenza vaccination coverage in Europe requires multi‐level, stakeholder‐specific strategies. These should include education campaigns, improved access through alternative delivery settings (e.g., pharmacies, schools), targeted communication to high‐risk and underserved populations, and systemic changes to support healthcare providers. Tackling these issues will help reduce preventable morbidity and mortality, enhance herd immunity, and foster healthier ageing across European populations.
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spelling doaj-art-8044e415db1148b38b6923b51b2826102025-07-31T06:40:38ZengWileyImmunity, Inflammation and Disease2050-45272025-07-01137n/an/a10.1002/iid3.70186Disparities in Seasonal Influenza Vaccination in EuropeKatinka M. Giezeman‐Smits0Bram Palache1Gerrit A. vanEssen2Miloš Jeseňák3Enrique Castro‐Sánchez4Anna Elisabeth Steinberg5Joris vanVugt6Viatris Turmstrasse 24 Steinhausen SwitzerlandFluPal Consultancy B.V. Bourgondischelaan 33 Amstelveen the NetherlandsDutch Influenza Foundation Paladijnenweg 30 Amersfoort the NetherlandsComenius University in Bratislava, University Hospital in Martin SlovakiaBrunel University London, College of Business, Arts and Social Sciences Uxbridge UKViatris Benzstraße 1 Bad Homburg vor der Höhe GermanyViatris Krijgsman 20 Amstelveen the NetherlandsABSTRACT Background Seasonal influenza remains a major public health challenge in Europe, associated with high morbidity, mortality, and socioeconomic burden. Despite the proven efficacy and cost‐effectiveness of vaccination, coverage rates vary substantially across European countries and population groups, often falling short of the World Health Organization's target of 75% for older adults. Objective This narrative review aims to identify and explore disparities in seasonal influenza vaccination coverage across European countries and among different population subgroups. It also seeks to examine the underlying causes of these disparities and propose actionable strategies to improve equity in vaccine uptake. Methods A literature search was conducted using the PubMed database for English‐language articles published within the last 5 years. Keywords included: comorbidity, disparity, Europe, inequality, influenza, knowledge, ethnic disparity, seasonal influenza vaccination, socioeconomic disparity, vaccination coverage, and vaccine hesitancy. Additional references were identified from the retrieved articles. Results Widespread disparities in influenza vaccination were observed across various demographic and professional groups. These included disparities by geographic location, ethnicity, socioeconomic status, sex and gender, age, comorbidities, and occupation—particularly among healthcare professionals. Contributing factors included limited knowledge or education, negative attitudes or behaviors toward vaccination, vaccine hesitancy and fatigue, and restricted access to vaccination services. Structural barriers and institutional trust issues also played key roles. Conclusions Addressing disparities in influenza vaccination coverage in Europe requires multi‐level, stakeholder‐specific strategies. These should include education campaigns, improved access through alternative delivery settings (e.g., pharmacies, schools), targeted communication to high‐risk and underserved populations, and systemic changes to support healthcare providers. Tackling these issues will help reduce preventable morbidity and mortality, enhance herd immunity, and foster healthier ageing across European populations.https://doi.org/10.1002/iid3.70186comorbidityethnic disparityinequalityinfluenzaseasonal influenza vaccinationvaccine access
spellingShingle Katinka M. Giezeman‐Smits
Bram Palache
Gerrit A. vanEssen
Miloš Jeseňák
Enrique Castro‐Sánchez
Anna Elisabeth Steinberg
Joris vanVugt
Disparities in Seasonal Influenza Vaccination in Europe
Immunity, Inflammation and Disease
comorbidity
ethnic disparity
inequality
influenza
seasonal influenza vaccination
vaccine access
title Disparities in Seasonal Influenza Vaccination in Europe
title_full Disparities in Seasonal Influenza Vaccination in Europe
title_fullStr Disparities in Seasonal Influenza Vaccination in Europe
title_full_unstemmed Disparities in Seasonal Influenza Vaccination in Europe
title_short Disparities in Seasonal Influenza Vaccination in Europe
title_sort disparities in seasonal influenza vaccination in europe
topic comorbidity
ethnic disparity
inequality
influenza
seasonal influenza vaccination
vaccine access
url https://doi.org/10.1002/iid3.70186
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AT milosjesenak disparitiesinseasonalinfluenzavaccinationineurope
AT enriquecastrosanchez disparitiesinseasonalinfluenzavaccinationineurope
AT annaelisabethsteinberg disparitiesinseasonalinfluenzavaccinationineurope
AT jorisvanvugt disparitiesinseasonalinfluenzavaccinationineurope