To Investigate the Relationship Between the Prognosis and Mortality of Intoxication Cases Admitted to The Emergency Department and Intoxication Severity Scoring Systems

Background: This study aimed to evaluate the need for intensive care unit (ICU) admission and the severity of intoxication in patients presenting to the Emergency Department (ED) using the Ankara Poisoning Criteria, PGI, Mascot, and Sequential Organ Failure Assessment (SOFA) scores.Methods: This pro...

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Main Authors: Ayşegül Uygur, Yahya Günaydın, Dilber Üçöz Kocaşaban
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-06-01
Series:Asia Pacific Journal of Medical Toxicology
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Online Access:https://apjmt.mums.ac.ir/article_26156_f32e74bb2821917210a7839330f68fd4.pdf
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author Ayşegül Uygur
Yahya Günaydın
Dilber Üçöz Kocaşaban
author_facet Ayşegül Uygur
Yahya Günaydın
Dilber Üçöz Kocaşaban
author_sort Ayşegül Uygur
collection DOAJ
description Background: This study aimed to evaluate the need for intensive care unit (ICU) admission and the severity of intoxication in patients presenting to the Emergency Department (ED) using the Ankara Poisoning Criteria, PGI, Mascot, and Sequential Organ Failure Assessment (SOFA) scores.Methods: This prospective observational study included intoxicated patients aged over 18 years who were admitted to the ED over a 1-year period. Demographic data, clinical parameters, and various intoxication scoring systems were used to assess poisoning severity and ICU admission needs. The diagnostic performance was evaluated using ROC curves, and risk factors for ICU admission were determined through univariate and multivariate logistic regression analyses.Results: A total of 210 patients were included. Half (n=105) were admitted to the ICU, and the other half were monitored in the ED. The median age was 30 years, and 52.9% of patients were male. Significant differences in age and Glasgow Coma Scale (GCS) scores were observed between ICU-admitted and ED-discharged patients (p<0.05). In multivariate analysis, age, Ankara Criteria scores, and Mascot scores were identified as independent risk factors for ICU admission (p<0.01). The Ankara Criteria demonstrated the highest diagnostic accuracy for predicting ICU admission.Conclusion: The Ankara Poisoning Criteria is a reliable and effective tool for assessing poisoning severity and predicting ICU admission.
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spelling doaj-art-7fc9ab5ba90d4fd89578049bcaa1e04d2025-07-01T06:28:23ZengMashhad University of Medical SciencesAsia Pacific Journal of Medical Toxicology2322-26112322-43202025-06-0114210.22038/apjmt.2025.84664.148926156To Investigate the Relationship Between the Prognosis and Mortality of Intoxication Cases Admitted to The Emergency Department and Intoxication Severity Scoring SystemsAyşegül Uygur0Yahya Günaydın1Dilber Üçöz Kocaşaban2Department of Emergency Medicine, University of Health Sciences, Ankara Training and Research Hospital, Ankara, TurkeyDepartment of Emergency Medicine, University of Health Sciences, Ankara Training and Research Hospital, Ankara, TurkeyDepartment of Emergency Medicine, University of Health Sciences, Ankara Training and Research Hospital, Ankara, TurkeyBackground: This study aimed to evaluate the need for intensive care unit (ICU) admission and the severity of intoxication in patients presenting to the Emergency Department (ED) using the Ankara Poisoning Criteria, PGI, Mascot, and Sequential Organ Failure Assessment (SOFA) scores.Methods: This prospective observational study included intoxicated patients aged over 18 years who were admitted to the ED over a 1-year period. Demographic data, clinical parameters, and various intoxication scoring systems were used to assess poisoning severity and ICU admission needs. The diagnostic performance was evaluated using ROC curves, and risk factors for ICU admission were determined through univariate and multivariate logistic regression analyses.Results: A total of 210 patients were included. Half (n=105) were admitted to the ICU, and the other half were monitored in the ED. The median age was 30 years, and 52.9% of patients were male. Significant differences in age and Glasgow Coma Scale (GCS) scores were observed between ICU-admitted and ED-discharged patients (p<0.05). In multivariate analysis, age, Ankara Criteria scores, and Mascot scores were identified as independent risk factors for ICU admission (p<0.01). The Ankara Criteria demonstrated the highest diagnostic accuracy for predicting ICU admission.Conclusion: The Ankara Poisoning Criteria is a reliable and effective tool for assessing poisoning severity and predicting ICU admission.https://apjmt.mums.ac.ir/article_26156_f32e74bb2821917210a7839330f68fd4.pdfemergency medicineintensive care unitspoisoningprediction
spellingShingle Ayşegül Uygur
Yahya Günaydın
Dilber Üçöz Kocaşaban
To Investigate the Relationship Between the Prognosis and Mortality of Intoxication Cases Admitted to The Emergency Department and Intoxication Severity Scoring Systems
Asia Pacific Journal of Medical Toxicology
emergency medicine
intensive care units
poisoning
prediction
title To Investigate the Relationship Between the Prognosis and Mortality of Intoxication Cases Admitted to The Emergency Department and Intoxication Severity Scoring Systems
title_full To Investigate the Relationship Between the Prognosis and Mortality of Intoxication Cases Admitted to The Emergency Department and Intoxication Severity Scoring Systems
title_fullStr To Investigate the Relationship Between the Prognosis and Mortality of Intoxication Cases Admitted to The Emergency Department and Intoxication Severity Scoring Systems
title_full_unstemmed To Investigate the Relationship Between the Prognosis and Mortality of Intoxication Cases Admitted to The Emergency Department and Intoxication Severity Scoring Systems
title_short To Investigate the Relationship Between the Prognosis and Mortality of Intoxication Cases Admitted to The Emergency Department and Intoxication Severity Scoring Systems
title_sort to investigate the relationship between the prognosis and mortality of intoxication cases admitted to the emergency department and intoxication severity scoring systems
topic emergency medicine
intensive care units
poisoning
prediction
url https://apjmt.mums.ac.ir/article_26156_f32e74bb2821917210a7839330f68fd4.pdf
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