To Investigate the Relationship Between the Prognosis and Mortality of Intoxication Cases Admitted to The Emergency Department and Intoxication Severity Scoring Systems

Background: This study aimed to evaluate the need for intensive care unit (ICU) admission and the severity of intoxication in patients presenting to the Emergency Department (ED) using the Ankara Poisoning Criteria, PGI, Mascot, and Sequential Organ Failure Assessment (SOFA) scores.Methods: This pro...

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Main Authors: Ayşegül Uygur, Yahya Günaydın, Dilber Üçöz Kocaşaban
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-06-01
Series:Asia Pacific Journal of Medical Toxicology
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Online Access:https://apjmt.mums.ac.ir/article_26156_f32e74bb2821917210a7839330f68fd4.pdf
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Summary:Background: This study aimed to evaluate the need for intensive care unit (ICU) admission and the severity of intoxication in patients presenting to the Emergency Department (ED) using the Ankara Poisoning Criteria, PGI, Mascot, and Sequential Organ Failure Assessment (SOFA) scores.Methods: This prospective observational study included intoxicated patients aged over 18 years who were admitted to the ED over a 1-year period. Demographic data, clinical parameters, and various intoxication scoring systems were used to assess poisoning severity and ICU admission needs. The diagnostic performance was evaluated using ROC curves, and risk factors for ICU admission were determined through univariate and multivariate logistic regression analyses.Results: A total of 210 patients were included. Half (n=105) were admitted to the ICU, and the other half were monitored in the ED. The median age was 30 years, and 52.9% of patients were male. Significant differences in age and Glasgow Coma Scale (GCS) scores were observed between ICU-admitted and ED-discharged patients (p<0.05). In multivariate analysis, age, Ankara Criteria scores, and Mascot scores were identified as independent risk factors for ICU admission (p<0.01). The Ankara Criteria demonstrated the highest diagnostic accuracy for predicting ICU admission.Conclusion: The Ankara Poisoning Criteria is a reliable and effective tool for assessing poisoning severity and predicting ICU admission.
ISSN:2322-2611
2322-4320