MECHANISMS OF ANTI-PROLIFERATIVE EFFECT PRODUCED BY MESENCHYMAL STEM CELLS IN PATIENTS WITH MULTIPLE SCLEROSIS

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MECHANISMS OF ANTI-PROLIFERATIVE EFFECT PRODUCED BY MESENCHYMAL STEM CELLS IN PATIENTS WITH MULTIPLE SCLEROSIS

Abstract. We investigated the ability of autologous/allogeneic mesenchymal stem cells (MSC) from early passages, derived from bone marrow of patients with multiple sclerosis, to inhibit mitogen/myelin-induced proliferation of memory T cells. It was shown that MSC immunosuppressive potenti...

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Bibliographic Details
Main Authors:	M. M. Zafranskaya, D. B. Nizhegorodova, M. Yu. Yurkevich, S. S. Bagatka, H. I. Ivanchyk, Yana M. Motuzova, A. S. Fedulov
Format:	Article
Language:	Russian
Published:	St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2014-07-01
Series:	Медицинская иммунология
Subjects:	immune suppression mesenchymal stem cells multiple sclerosis prostaglandin e2 indoleamine 2 3-dioxygenase
Online Access:	https://www.mimmun.ru/mimmun/article/view/455
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