Arid1a deficiency sensitises pancreatic cancer to fatty acid synthase inhibition

Abstract Background Mutations in the AT‐rich interactive domain‐containing protein 1A (ARID1A) gene are frequently found in pancreatic cancer. However, the contribution of ARID1A inactivation to pancreatic tumorigenesis remains unclear. Previous work showed that depletion of Arid1a at early developm...

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Bibliographic Details
Main Authors: Tzu‐Lei Kuo, Ya‐Chin Hou, Yan‐Shen Shan, Li‐Tzong Chen, Wen‐Chun Hung
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Clinical and Translational Medicine
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Online Access:https://doi.org/10.1002/ctm2.70394
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