Molecular Epidemiology and the Control and Prevention of Cystic Echinococcosis in China: What is Known from Current Research
<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d1446443e174">As a zoonotic parasitic disease, echinococcosis is a severe global public health issue caused by the larvae of <i>Echinococ...
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2023-04-01
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| Series: | Zoonoses |
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| author | Ying Wang Jing Zhang Xu Wang Haroon Ahmed Yujuan Shen Jianping Cao |
| author_facet | Ying Wang Jing Zhang Xu Wang Haroon Ahmed Yujuan Shen Jianping Cao |
| author_sort | Ying Wang |
| collection | DOAJ |
| description | <p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d1446443e174">As a zoonotic parasitic disease, echinococcosis is a severe global public health issue
caused by the larvae of
<i>Echinococcus</i> spp. Not only does echinococcosis threaten human health, but echinococcosis also
causes enormous economic losses. China ranks first in the range of echinococcosis
endemic areas, the number of infected patients, and the number of threatened populations
worldwide, hence the most severe echinococcosis epidemic currently exists in China.
Cystic echinococcosis (CE) is the most important form of echinococcosis. Accounting
for nearly 80% of all echinococcosis cases, CE is the most important cause of the
echinococcosis disease burden.
<i>Echinococcus granulosus sensu lato</i> (
<i>s.l.</i>) is the causative agent of CE and is considered a multi-genotype complex. The different
genotypes of
<i>E. granulosus s.l.</i> exhibit differences in morphology, transmission route, and epidemic characteristics.
The corresponding clinical characteristics, clinical treatment, and vaccine responses
also differ between the genotypes of
<i>E. granulosus s.l.</i> During the past two decades, China has implemented echinococcosis control and prevention
programs in endemic areas with impressive results. Specifically, the prevalence of
echinococcosis has decreased. With such extraordinary achievements, precise control
and prevention of the genotypes of
<i>E. granulosus s.l.</i> have never been more important. Nevertheless, insufficient attention has been devoted
to molecular epidemiology in the current control programs, and the lack of genotype
data from humans and animal hosts exacerbates the situation. Hence, based on the ongoing
control and surveillance programs, collecting additional molecular epidemiologic data
and geographic information from humans and animals, as well as monitoring the clinical
manifestations and drug and vaccine responses of the different genotypes, are invaluable
for establishing a molecular epidemiologic database, which in turn can enhance the
precise control and prevention of echinococcosis.
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| format | Article |
| id | doaj-art-7dfc5444d8a14a2d80aee0b4e90d76f7 |
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| issn | 2737-7466 2737-7474 |
| language | English |
| publishDate | 2023-04-01 |
| publisher | Compuscript Ltd |
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| series | Zoonoses |
| spelling | doaj-art-7dfc5444d8a14a2d80aee0b4e90d76f72025-07-10T16:00:09ZengCompuscript LtdZoonoses2737-74662737-74742023-04-013197610.15212/ZOONOSES-2023-0009Molecular Epidemiology and the Control and Prevention of Cystic Echinococcosis in China: What is Known from Current ResearchYing WangJing ZhangXu WangHaroon AhmedYujuan ShenJianping Cao<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d1446443e174">As a zoonotic parasitic disease, echinococcosis is a severe global public health issue caused by the larvae of <i>Echinococcus</i> spp. Not only does echinococcosis threaten human health, but echinococcosis also causes enormous economic losses. China ranks first in the range of echinococcosis endemic areas, the number of infected patients, and the number of threatened populations worldwide, hence the most severe echinococcosis epidemic currently exists in China. Cystic echinococcosis (CE) is the most important form of echinococcosis. Accounting for nearly 80% of all echinococcosis cases, CE is the most important cause of the echinococcosis disease burden. <i>Echinococcus granulosus sensu lato</i> ( <i>s.l.</i>) is the causative agent of CE and is considered a multi-genotype complex. The different genotypes of <i>E. granulosus s.l.</i> exhibit differences in morphology, transmission route, and epidemic characteristics. The corresponding clinical characteristics, clinical treatment, and vaccine responses also differ between the genotypes of <i>E. granulosus s.l.</i> During the past two decades, China has implemented echinococcosis control and prevention programs in endemic areas with impressive results. Specifically, the prevalence of echinococcosis has decreased. With such extraordinary achievements, precise control and prevention of the genotypes of <i>E. granulosus s.l.</i> have never been more important. Nevertheless, insufficient attention has been devoted to molecular epidemiology in the current control programs, and the lack of genotype data from humans and animal hosts exacerbates the situation. Hence, based on the ongoing control and surveillance programs, collecting additional molecular epidemiologic data and geographic information from humans and animals, as well as monitoring the clinical manifestations and drug and vaccine responses of the different genotypes, are invaluable for establishing a molecular epidemiologic database, which in turn can enhance the precise control and prevention of echinococcosis. </p>https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2023-0009 |
| spellingShingle | Ying Wang Jing Zhang Xu Wang Haroon Ahmed Yujuan Shen Jianping Cao Molecular Epidemiology and the Control and Prevention of Cystic Echinococcosis in China: What is Known from Current Research Zoonoses |
| title | Molecular Epidemiology and the Control and Prevention of Cystic Echinococcosis in China: What is Known from Current Research |
| title_full | Molecular Epidemiology and the Control and Prevention of Cystic Echinococcosis in China: What is Known from Current Research |
| title_fullStr | Molecular Epidemiology and the Control and Prevention of Cystic Echinococcosis in China: What is Known from Current Research |
| title_full_unstemmed | Molecular Epidemiology and the Control and Prevention of Cystic Echinococcosis in China: What is Known from Current Research |
| title_short | Molecular Epidemiology and the Control and Prevention of Cystic Echinococcosis in China: What is Known from Current Research |
| title_sort | molecular epidemiology and the control and prevention of cystic echinococcosis in china what is known from current research |
| url | https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2023-0009 |
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