Comprehensive immune ageing reveals TREM2/TIM3 myeloid cells drive brain immune evasionResearch in context

Comprehensive immune ageing reveals TREM2/TIM3 myeloid cells drive brain immune evasionResearch in context

Summary: Background: Ageing-dependent low-grade inflammation is a hallmark of central nervous system (CNS) diseases. Vascular and immune abnormalities are implicated in the progression of gliomas and occur in the early stages of Alzheimer's disease (AD); however, the mechanisms by which these...

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Main Authors: Berta Segura-Collar, Lucia Mondejar-Ruescas, Denisse Alcivar-López, María Garranzo-Asensio, Pablo Mata-Martinez, Ramón Garcia-Escudero, Aurelio Hernández-Laín, Juan M. Sepúlveda, Ángel Pérez Nuñez, Jesús Avila, Pilar Sánchez-Gómez, Ricardo Gargini
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:EBioMedicine
Subjects:
Glioblastoma
Ageing
Alzheimer's disease
Immune evasion
TREM2
TIM3
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425002774
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