Clinical features of the course of overt diabetes mellitus during pregnancy
Objective: to analyze the features of diagnosis, course and outcomes of pregnancy in women with manifest diabetes mellitus.Materials and methods: the study included 19 delivery medical records of women with MDM (manifest diabetes mellitus during pregnancy) and 500 records of women with GDM (gestatio...
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| Format: | Article |
| Language: | English |
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State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation
2022-03-01
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| Series: | Медицинский вестник Юга России |
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| Online Access: | https://www.medicalherald.ru/jour/article/view/1488 |
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| author | A. V. Tiselko M. K. Tsyganova M. I. Yarmolinskaya T. A. Zinina |
| author_facet | A. V. Tiselko M. K. Tsyganova M. I. Yarmolinskaya T. A. Zinina |
| author_sort | A. V. Tiselko |
| collection | DOAJ |
| description | Objective: to analyze the features of diagnosis, course and outcomes of pregnancy in women with manifest diabetes mellitus.Materials and methods: the study included 19 delivery medical records of women with MDM (manifest diabetes mellitus during pregnancy) and 500 records of women with GDM (gestational diabetes mellitus).Results: Th irteen women out of nineteen were diagnosed with MDM in the fi rst half of pregnancy. Th e average level of glycemia at the onset of the disease was 9,3±3,0 mmol/l. Mean HbA1c was 7,2±1,1%, which signifi cantly exceeded this indicator in GDM. All women with MDM required insulin therapy, while in the group of women with GDM insulin therapy was used in 27.8% of cases. MDM women showed increased rates of preeclampsia (36,8%) compared to GDM women (15%). Fetal macrosomia was more common in MDM women (36.8%) than in GDM women (17%).Conclusion: Th e high frequency of obstetric and perinatal complications of MDM during pregnancy requires the early detection of hyperglycemia and the prompt initiation of insulin therapy. Screening for carbohydrate metabolism disorders at the fi rst prenatal visit and early initiation of insulin therapy reduce maternal and perinatal mortality. |
| format | Article |
| id | doaj-art-7da3ba9b9ae54a9ca60e56f52bd74e1c |
| institution | Matheson Library |
| issn | 2219-8075 2618-7876 |
| language | English |
| publishDate | 2022-03-01 |
| publisher | State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation |
| record_format | Article |
| series | Медицинский вестник Юга России |
| spelling | doaj-art-7da3ba9b9ae54a9ca60e56f52bd74e1c2025-07-03T16:13:40ZengState Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian FederationМедицинский вестник Юга России2219-80752618-78762022-03-01131808710.21886/2219-8075-2022-13-1-80-87859Clinical features of the course of overt diabetes mellitus during pregnancyA. V. Tiselko0M. K. Tsyganova1M. I. Yarmolinskaya2T. A. Zinina3D.O. Ott Research institute of Obstetrics, Gynecology, and ReproductologySaint Petersburg state universityD.O. Ott Research institute of Obstetrics, Gynecology, and Reproductology; I.I. Mechnikov North-Western state medical UniversityWomen’s Consultation No. 22Objective: to analyze the features of diagnosis, course and outcomes of pregnancy in women with manifest diabetes mellitus.Materials and methods: the study included 19 delivery medical records of women with MDM (manifest diabetes mellitus during pregnancy) and 500 records of women with GDM (gestational diabetes mellitus).Results: Th irteen women out of nineteen were diagnosed with MDM in the fi rst half of pregnancy. Th e average level of glycemia at the onset of the disease was 9,3±3,0 mmol/l. Mean HbA1c was 7,2±1,1%, which signifi cantly exceeded this indicator in GDM. All women with MDM required insulin therapy, while in the group of women with GDM insulin therapy was used in 27.8% of cases. MDM women showed increased rates of preeclampsia (36,8%) compared to GDM women (15%). Fetal macrosomia was more common in MDM women (36.8%) than in GDM women (17%).Conclusion: Th e high frequency of obstetric and perinatal complications of MDM during pregnancy requires the early detection of hyperglycemia and the prompt initiation of insulin therapy. Screening for carbohydrate metabolism disorders at the fi rst prenatal visit and early initiation of insulin therapy reduce maternal and perinatal mortality.https://www.medicalherald.ru/jour/article/view/1488manifest diabetes mellitusgestational diabetes mellituspreeclampsiadiabetic fetopathyinsulin therapy |
| spellingShingle | A. V. Tiselko M. K. Tsyganova M. I. Yarmolinskaya T. A. Zinina Clinical features of the course of overt diabetes mellitus during pregnancy Медицинский вестник Юга России manifest diabetes mellitus gestational diabetes mellitus preeclampsia diabetic fetopathy insulin therapy |
| title | Clinical features of the course of overt diabetes mellitus during pregnancy |
| title_full | Clinical features of the course of overt diabetes mellitus during pregnancy |
| title_fullStr | Clinical features of the course of overt diabetes mellitus during pregnancy |
| title_full_unstemmed | Clinical features of the course of overt diabetes mellitus during pregnancy |
| title_short | Clinical features of the course of overt diabetes mellitus during pregnancy |
| title_sort | clinical features of the course of overt diabetes mellitus during pregnancy |
| topic | manifest diabetes mellitus gestational diabetes mellitus preeclampsia diabetic fetopathy insulin therapy |
| url | https://www.medicalherald.ru/jour/article/view/1488 |
| work_keys_str_mv | AT avtiselko clinicalfeaturesofthecourseofovertdiabetesmellitusduringpregnancy AT mktsyganova clinicalfeaturesofthecourseofovertdiabetesmellitusduringpregnancy AT miyarmolinskaya clinicalfeaturesofthecourseofovertdiabetesmellitusduringpregnancy AT tazinina clinicalfeaturesofthecourseofovertdiabetesmellitusduringpregnancy |