PKN2 Inhibits VEGFA and bFGF‐Mediated Angiogenesis by Targeting HIF‐1α in Colon Cancer

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PKN2 Inhibits VEGFA and bFGF‐Mediated Angiogenesis by Targeting HIF‐1α in Colon Cancer

ABSTRACT Angiogenesis plays a vital role in colon cancer growth and metastasis. The role of protein kinase N2 (PKN2) in colon cancer is rarely studied. In this study, we investigated the effect of PKN2 on angiogenesis in colon cancer. We evaluated the correlation between PKN2 expression and microves...

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Bibliographic Details
Main Authors:	Yun Zhu, Shi‐Yun Huang, Yi Lei, An‐Ni Luo, Xiang‐Zhao Li, Biao Wang, Peng‐Hui Sun, Si‐Tang Gong, Yang Cheng
Format:	Article
Language:	English
Published:	Wiley 2025-07-01
Series:	Kaohsiung Journal of Medical Sciences
Subjects:	colon cancer HIF‐1α PKN2 tumor angiogenesis
Online Access:	https://doi.org/10.1002/kjm2.70050
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