ACK1 condensates promote STAT5 signaling in lung squamous cell carcinoma
Abstract Background ACK1, a non-receptor tyrosine kinase, phosphorylates various substrates involved in cancer progression. Its oncogenic activity is driven by gene amplification, mutations, and post-translational modifications. However, additional regulatory mechanisms that govern ACK1 activity rem...
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Main Authors: | Andong Liu, Xia Lu, Yanyang Song, Jiaying Pei, Ruozheng Wei |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-06-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12935-025-03862-3 |
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