ACK1 condensates promote STAT5 signaling in lung squamous cell carcinoma

Abstract Background ACK1, a non-receptor tyrosine kinase, phosphorylates various substrates involved in cancer progression. Its oncogenic activity is driven by gene amplification, mutations, and post-translational modifications. However, additional regulatory mechanisms that govern ACK1 activity rem...

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Bibliographic Details
Main Authors: Andong Liu, Xia Lu, Yanyang Song, Jiaying Pei, Ruozheng Wei
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cancer Cell International
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Online Access:https://doi.org/10.1186/s12935-025-03862-3
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