Synergies of dibutyl phthalate on high-fat diet can aggravate cardiac fibrosis/dysfunction and the protective effects of vitamin E and salidroside: A molecular toxicological study in Sprague-Dawley rats

Synergies of dibutyl phthalate on high-fat diet can aggravate cardiac fibrosis/dysfunction and the protective effects of vitamin E and salidroside: A molecular toxicological study in Sprague-Dawley rats

Background: Dibutyl phthalate (DBP) is a pollutant associated with plastic contamination and is commonly used as a plasticizer. It is linked to various adverse health effects, including cardiovascular disease (CVD). There is an association between DBP and high-fat diet (HFD), with HFD also contribut...

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Bibliographic Details
Main Authors: Xiao Liang, Yang Wu, Qing Feng, Deyu Zhu, Qi Huang, Zhuangzhuang Wei, Ping Ma, Xu Yang, Cuiyu Bao, Xinyu Bao
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Plastic-pollution derivative
Dibutyl phthalate
High fat diet
Cardiac fibrosis
Cardiac dysfunction
Pyroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S014765132501053X
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