Risk Factors for Hemorrhagic Stroke in Patients Admitted to the Emergency Department: A Retrospective Cross-sectional Study
Background: Hemorrhagic strokes accounting for 10%–20% of all strokes. This study aims to assess the medical and laboratory profiles of patients with hemorrhagic stroke to identify risk factors and predictors of mortality. Methods: In this retrospective study, the complete medical records of patient...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-04-01
|
| Series: | Biomedical and Biotechnology Research Journal |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/bbrj.bbrj_186_25 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1839639722193846272 |
|---|---|
| author | Mandana Pouladzadeh Hesam Hoveizavi Mofid Hosseinzadeh |
| author_facet | Mandana Pouladzadeh Hesam Hoveizavi Mofid Hosseinzadeh |
| author_sort | Mandana Pouladzadeh |
| collection | DOAJ |
| description | Background:
Hemorrhagic strokes accounting for 10%–20% of all strokes. This study aims to assess the medical and laboratory profiles of patients with hemorrhagic stroke to identify risk factors and predictors of mortality.
Methods:
In this retrospective study, the complete medical records of patients with hemorrhagic stroke who were referred to the emergency department of the hospital in 2022 were reviewed. Demographic information (age and sex), clinical data, and laboratory findings on the day of admission were collected for statistical analyses.
Results:
A total of 285 patients with hemorrhagic stroke were evaluated, comprising 190 males and 95 females. The mean age of men was significantly higher than women (P = 0.001). Moreover, the disease incidence was notably higher in men and among patients aged 60 years and older (P = 0.0001). The most common comorbidities included hypertension (70.2%), diabetes (36.1%), inactivity (35.1%), and cardiac ischemia (31.2%). Anemia, defined by abnormally low hemoglobin levels, was present in 76.5% of patients and correlated with the incidence of hemorrhagic stroke (P = 0.0001). In addition, 89.47% of patients had hyperglycemia, which was also associated with hemorrhagic stroke (P = 0.0001). However, other biomarkers showed no significant correlation (P > 0.05). Notably, thrombocytopenia was significantly linked to a higher risk of death (hazard ratio [95% confidence interval CI]: 0.998 [0.996–1], P = 0.03).
Conclusion:
Male sex, older age, comorbidities, previous stroke, anemia, hyperglycemia, and thrombocytopenia are identified as risk factors for hemorrhagic stroke. Furthermore, thrombocytopenia seems to be associated with high risk of death in these patients, underscoring the need for its timely treatment. |
| format | Article |
| id | doaj-art-7b966bae91c84c5a8d520f8c63f25819 |
| institution | Matheson Library |
| issn | 2588-9834 2588-9842 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Biomedical and Biotechnology Research Journal |
| spelling | doaj-art-7b966bae91c84c5a8d520f8c63f258192025-07-04T06:06:18ZengWolters Kluwer Medknow PublicationsBiomedical and Biotechnology Research Journal2588-98342588-98422025-04-019212513110.4103/bbrj.bbrj_186_25Risk Factors for Hemorrhagic Stroke in Patients Admitted to the Emergency Department: A Retrospective Cross-sectional StudyMandana PouladzadehHesam HoveizaviMofid HosseinzadehBackground: Hemorrhagic strokes accounting for 10%–20% of all strokes. This study aims to assess the medical and laboratory profiles of patients with hemorrhagic stroke to identify risk factors and predictors of mortality. Methods: In this retrospective study, the complete medical records of patients with hemorrhagic stroke who were referred to the emergency department of the hospital in 2022 were reviewed. Demographic information (age and sex), clinical data, and laboratory findings on the day of admission were collected for statistical analyses. Results: A total of 285 patients with hemorrhagic stroke were evaluated, comprising 190 males and 95 females. The mean age of men was significantly higher than women (P = 0.001). Moreover, the disease incidence was notably higher in men and among patients aged 60 years and older (P = 0.0001). The most common comorbidities included hypertension (70.2%), diabetes (36.1%), inactivity (35.1%), and cardiac ischemia (31.2%). Anemia, defined by abnormally low hemoglobin levels, was present in 76.5% of patients and correlated with the incidence of hemorrhagic stroke (P = 0.0001). In addition, 89.47% of patients had hyperglycemia, which was also associated with hemorrhagic stroke (P = 0.0001). However, other biomarkers showed no significant correlation (P > 0.05). Notably, thrombocytopenia was significantly linked to a higher risk of death (hazard ratio [95% confidence interval CI]: 0.998 [0.996–1], P = 0.03). Conclusion: Male sex, older age, comorbidities, previous stroke, anemia, hyperglycemia, and thrombocytopenia are identified as risk factors for hemorrhagic stroke. Furthermore, thrombocytopenia seems to be associated with high risk of death in these patients, underscoring the need for its timely treatment.https://journals.lww.com/10.4103/bbrj.bbrj_186_25anemiahemorrhagic strokehyperglycemiamortalitythrombocytopenia |
| spellingShingle | Mandana Pouladzadeh Hesam Hoveizavi Mofid Hosseinzadeh Risk Factors for Hemorrhagic Stroke in Patients Admitted to the Emergency Department: A Retrospective Cross-sectional Study Biomedical and Biotechnology Research Journal anemia hemorrhagic stroke hyperglycemia mortality thrombocytopenia |
| title | Risk Factors for Hemorrhagic Stroke in Patients Admitted to the Emergency Department: A Retrospective Cross-sectional Study |
| title_full | Risk Factors for Hemorrhagic Stroke in Patients Admitted to the Emergency Department: A Retrospective Cross-sectional Study |
| title_fullStr | Risk Factors for Hemorrhagic Stroke in Patients Admitted to the Emergency Department: A Retrospective Cross-sectional Study |
| title_full_unstemmed | Risk Factors for Hemorrhagic Stroke in Patients Admitted to the Emergency Department: A Retrospective Cross-sectional Study |
| title_short | Risk Factors for Hemorrhagic Stroke in Patients Admitted to the Emergency Department: A Retrospective Cross-sectional Study |
| title_sort | risk factors for hemorrhagic stroke in patients admitted to the emergency department a retrospective cross sectional study |
| topic | anemia hemorrhagic stroke hyperglycemia mortality thrombocytopenia |
| url | https://journals.lww.com/10.4103/bbrj.bbrj_186_25 |
| work_keys_str_mv | AT mandanapouladzadeh riskfactorsforhemorrhagicstrokeinpatientsadmittedtotheemergencydepartmentaretrospectivecrosssectionalstudy AT hesamhoveizavi riskfactorsforhemorrhagicstrokeinpatientsadmittedtotheemergencydepartmentaretrospectivecrosssectionalstudy AT mofidhosseinzadeh riskfactorsforhemorrhagicstrokeinpatientsadmittedtotheemergencydepartmentaretrospectivecrosssectionalstudy |