Chemical decellularization of porcine liver by two-stage treatment with surfactants and osmoregulators enhances preservation of liver extracellular matrix structure

Chemical decellularization of porcine liver by two-stage treatment with surfactants and osmoregulators enhances preservation of liver extracellular matrix structure

Objective: to develop and investigate a tissue-specific matrix obtained using a modified chemical porcine liver decellularization regime in order to effectively increase preservation of extracellular matrix (ECM) structure, reduce decellularization time and improve purification of the ECM from cellu...

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Bibliographic Details
Main Authors: A. D. Belova, E. A. Nemets, D. D. Filin, A. S. Ponomareva, L. A. Kirsanova, Yu. B. Basok, V. I. Sevastianov
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2025-03-01
Series:Вестник трансплантологии и искусственных органов
Subjects:
porcine liver
decellularization
glycosaminoglycans
tissue engineering
Online Access:https://journal.transpl.ru/vtio/article/view/1869
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