Integrated multi-omics and machine learning reveal an immunogenic cell death-related signature for prognostic stratification and therapeutic optimization in colorectal cancer

Colorectal cancer (CRC) continues to rise in global incidence and remains a leading cause of cancer-related mortality. Immunogenic cell death (ICD) has emerged as a critical modulator of tumor microenvironment (TME) dynamics; however, its prognostic implications and therapeutic potential in CRC requ...

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Bibliographic Details
Main Authors: Siyu Hou, Shanshan Heng, Shaozhuo Xie, Yuanchun Zhao, Jiajia Chen, Chunjiang Yu, Yuxin Lin, Xin Qi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1606874/full
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