Short- and long-term results of organ-sparing surgery in patients with severe diffuse adenomyosis at perimenopausal transition

Aim. To study the short- and long-term results of organ-sparing surgery in patients with severe diffuse adenomyosis who are in the perimenopausal age.Materials and Methods. The study included 18 patients with severe diffuse adenomyosis who underwent fertility-sparing excision of diffuse adenomyosis...

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Main Authors: V. B. Tskhay, G. T. Mikailly, I. I. Tskhay
Format: Article
Language:Russian
Published: Kemerovo State Medical University 2023-04-01
Series:Фундаментальная и клиническая медицина
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Online Access:https://fcm.kemsmu.ru/jour/article/view/680
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author V. B. Tskhay
G. T. Mikailly
I. I. Tskhay
author_facet V. B. Tskhay
G. T. Mikailly
I. I. Tskhay
author_sort V. B. Tskhay
collection DOAJ
description Aim. To study the short- and long-term results of organ-sparing surgery in patients with severe diffuse adenomyosis who are in the perimenopausal age.Materials and Methods. The study included 18 patients with severe diffuse adenomyosis who underwent fertility-sparing excision of diffuse adenomyosis by means of Osada procedure. Efficiency of surgical treatment and subsequent drug therapy was evaluated at 12 and 24 months of follow-up by pelvic ultrasound examination. The frequency of adenomyosis symptoms and quality of life were assessed using the standard SF-36 questionnaire.Results. Recovery of the menstrual cycle, freedom from pain and anemia, and improved quality of life were documented in all cases (18/18), whereas onset of menopause occurred in half of the cases (9/18). In particular, all scales of the Physical Component Summary from SF-36 questionnaire were significantly improved at both follow-up time points.Conclusion. Organ-sparing excision of diffuse adenomyosis using Osada procedure is the option of choice and might represent an alternative to hysterectomy in women with perimenopausal age, in addition to those of earlier reproductive age.
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series Фундаментальная и клиническая медицина
spelling doaj-art-760117ad2b2a4f518457b51b44390ab62025-08-03T12:59:25ZrusKemerovo State Medical UniversityФундаментальная и клиническая медицина2500-07642542-09412023-04-01819310010.23946/2500-0764-2023-8-1-93-100357Short- and long-term results of organ-sparing surgery in patients with severe diffuse adenomyosis at perimenopausal transitionV. B. Tskhay0G. T. Mikailly1I. I. Tskhay2Voino-Yasenetsky Krasnoyarsk State Medical University; Federal Siberian Research Clinical Centre, Federal Medical-Biological AgencyVoino-Yasenetsky Krasnoyarsk State Medical University; Regional Clinical Center for Maternal and Child HealthFederal Siberian UniversityAim. To study the short- and long-term results of organ-sparing surgery in patients with severe diffuse adenomyosis who are in the perimenopausal age.Materials and Methods. The study included 18 patients with severe diffuse adenomyosis who underwent fertility-sparing excision of diffuse adenomyosis by means of Osada procedure. Efficiency of surgical treatment and subsequent drug therapy was evaluated at 12 and 24 months of follow-up by pelvic ultrasound examination. The frequency of adenomyosis symptoms and quality of life were assessed using the standard SF-36 questionnaire.Results. Recovery of the menstrual cycle, freedom from pain and anemia, and improved quality of life were documented in all cases (18/18), whereas onset of menopause occurred in half of the cases (9/18). In particular, all scales of the Physical Component Summary from SF-36 questionnaire were significantly improved at both follow-up time points.Conclusion. Organ-sparing excision of diffuse adenomyosis using Osada procedure is the option of choice and might represent an alternative to hysterectomy in women with perimenopausal age, in addition to those of earlier reproductive age.https://fcm.kemsmu.ru/jour/article/view/680diffuse adenomyosissurgical treatmentadenomyomectomylate reproductive ageperimenopausal agequality of life
spellingShingle V. B. Tskhay
G. T. Mikailly
I. I. Tskhay
Short- and long-term results of organ-sparing surgery in patients with severe diffuse adenomyosis at perimenopausal transition
Фундаментальная и клиническая медицина
diffuse adenomyosis
surgical treatment
adenomyomectomy
late reproductive age
perimenopausal age
quality of life
title Short- and long-term results of organ-sparing surgery in patients with severe diffuse adenomyosis at perimenopausal transition
title_full Short- and long-term results of organ-sparing surgery in patients with severe diffuse adenomyosis at perimenopausal transition
title_fullStr Short- and long-term results of organ-sparing surgery in patients with severe diffuse adenomyosis at perimenopausal transition
title_full_unstemmed Short- and long-term results of organ-sparing surgery in patients with severe diffuse adenomyosis at perimenopausal transition
title_short Short- and long-term results of organ-sparing surgery in patients with severe diffuse adenomyosis at perimenopausal transition
title_sort short and long term results of organ sparing surgery in patients with severe diffuse adenomyosis at perimenopausal transition
topic diffuse adenomyosis
surgical treatment
adenomyomectomy
late reproductive age
perimenopausal age
quality of life
url https://fcm.kemsmu.ru/jour/article/view/680
work_keys_str_mv AT vbtskhay shortandlongtermresultsoforgansparingsurgeryinpatientswithseverediffuseadenomyosisatperimenopausaltransition
AT gtmikailly shortandlongtermresultsoforgansparingsurgeryinpatientswithseverediffuseadenomyosisatperimenopausaltransition
AT iitskhay shortandlongtermresultsoforgansparingsurgeryinpatientswithseverediffuseadenomyosisatperimenopausaltransition