Hydrogen peroxide influence on contractile activity smooth muscle cells: the role of cytoskeleton
The influence of of hydrogen peroxide on the contractile reactions of smooth muscle cells caused by hyperpotassium solution end phenylephrine in modulation a potassium conductance the membrane and the state of cytoskeleton elements has been investigated by the mechanographical method. It has multidi...
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Format: | Article |
Language: | English |
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Siberian State Medical University (Tomsk)
2009-08-01
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Series: | Бюллетень сибирской медицины |
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Online Access: | https://bulletin.ssmu.ru/jour/article/view/1885 |
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author | I. V. Kovalyev S. V. Gusakova O. S. Melnik M. B. Baskakov L. V. Kapilevich M. A. Medvedev V. B. Studnitsky O. I. Antonov |
author_facet | I. V. Kovalyev S. V. Gusakova O. S. Melnik M. B. Baskakov L. V. Kapilevich M. A. Medvedev V. B. Studnitsky O. I. Antonov |
author_sort | I. V. Kovalyev |
collection | DOAJ |
description | The influence of of hydrogen peroxide on the contractile reactions of smooth muscle cells caused by hyperpotassium solution end phenylephrine in modulation a potassium conductance the membrane and the state of cytoskeleton elements has been investigated by the mechanographical method. It has multidirectional influence of hydrogen peroxide in the reduction of smooth muscles of rat aorta with the membrane depolarization hyperpotassium solution and action phenylephrine: phenylephrine decline in value and increase strength hyperpotassium contractures. We show that the cytoskeleton components involved in the mechanisms of action of hydrogen peroxide in the contractile reactions of smooth muscles of rat aorta caused by phenylephrine. |
format | Article |
id | doaj-art-73b363f6ba4f4e8c890e93ea2d2e4384 |
institution | Matheson Library |
issn | 1682-0363 1819-3684 |
language | English |
publishDate | 2009-08-01 |
publisher | Siberian State Medical University (Tomsk) |
record_format | Article |
series | Бюллетень сибирской медицины |
spelling | doaj-art-73b363f6ba4f4e8c890e93ea2d2e43842025-08-04T16:45:29ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842009-08-0184414610.20538/1682-0363-2009-4-41-461379Hydrogen peroxide influence on contractile activity smooth muscle cells: the role of cytoskeletonI. V. Kovalyev0S. V. Gusakova1O. S. Melnik2M. B. Baskakov3L. V. Kapilevich4M. A. Medvedev5V. B. Studnitsky6O. I. Antonov7Сибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетThe influence of of hydrogen peroxide on the contractile reactions of smooth muscle cells caused by hyperpotassium solution end phenylephrine in modulation a potassium conductance the membrane and the state of cytoskeleton elements has been investigated by the mechanographical method. It has multidirectional influence of hydrogen peroxide in the reduction of smooth muscles of rat aorta with the membrane depolarization hyperpotassium solution and action phenylephrine: phenylephrine decline in value and increase strength hyperpotassium contractures. We show that the cytoskeleton components involved in the mechanisms of action of hydrogen peroxide in the contractile reactions of smooth muscles of rat aorta caused by phenylephrine.https://bulletin.ssmu.ru/jour/article/view/1885smooth muscle cellscytoskeletonreactive oxygen specieshydrogen peroxide |
spellingShingle | I. V. Kovalyev S. V. Gusakova O. S. Melnik M. B. Baskakov L. V. Kapilevich M. A. Medvedev V. B. Studnitsky O. I. Antonov Hydrogen peroxide influence on contractile activity smooth muscle cells: the role of cytoskeleton Бюллетень сибирской медицины smooth muscle cells cytoskeleton reactive oxygen species hydrogen peroxide |
title | Hydrogen peroxide influence on contractile activity smooth muscle cells: the role of cytoskeleton |
title_full | Hydrogen peroxide influence on contractile activity smooth muscle cells: the role of cytoskeleton |
title_fullStr | Hydrogen peroxide influence on contractile activity smooth muscle cells: the role of cytoskeleton |
title_full_unstemmed | Hydrogen peroxide influence on contractile activity smooth muscle cells: the role of cytoskeleton |
title_short | Hydrogen peroxide influence on contractile activity smooth muscle cells: the role of cytoskeleton |
title_sort | hydrogen peroxide influence on contractile activity smooth muscle cells the role of cytoskeleton |
topic | smooth muscle cells cytoskeleton reactive oxygen species hydrogen peroxide |
url | https://bulletin.ssmu.ru/jour/article/view/1885 |
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