Chronic central nervous system aspergillosis with coexisting GFAP and AQP4 antibody positivity: case report and literature review

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Chronic central nervous system aspergillosis with coexisting GFAP and AQP4 antibody positivity: case report and literature review

This article presents an unusual case of chronic central nervous system (CNS) aspergillosis with concurrent glial fibrillary acidic protein (GFAP)-IgG and aquaporin-4 (AQP4)-IgG seropositivity. The patient presented with progressive numbness and weakness of the extremities over three months. The dia...

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Bibliographic Details
Main Authors:	Yimin Cao, Xueying Zhao, Shengpu Hao, Haiqing Yang, Duo Gao, Shixuan Du, Liang Wang, LiXia Zhou
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Immunology
Subjects:	autoimmune antibodies central nervous system aspergillosis immunity aquaporin-4 antibody glial fibrillary acidic protein antibody
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1613142/full
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