Global Epidemiology and Antimicrobial Resistance of Klebsiella Pneumoniae Carbapenemase (KPC)-Producing Gram-Negative Clinical Isolates: A Review

Global Epidemiology and Antimicrobial Resistance of Klebsiella Pneumoniae Carbapenemase (KPC)-Producing Gram-Negative Clinical Isolates: A Review

<i>Klebsiella pneumoniae</i> carbapenemases (KPCs) are a group of class A β-lactamases of Gram-negative bacteria leading to difficult-to-treat infections. We evaluated the global epidemiology of KPC-producing Gram-negative clinical isolates. A systematic search of six databases (Cochrane...

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Bibliographic Details
Main Authors: Matthew E. Falagas, Christina-Maria Asimotou, Maria Zidrou, Dimitrios S. Kontogiannis, Charalampos Filippou
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Microorganisms
Subjects:
<i>Klebsiella pneumoniae</i> carbapenemase (KPC)
Gram-negative
global epidemiology
global dissemination
β-lactamase
Online Access:https://www.mdpi.com/2076-2607/13/7/1697
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