EFFECTS OF DATE PALM POLLEN EXTRACT (PHOENIX DACTYLIFERA L.) ON REPRODUCTIVE FUNCTION IN RATS
Background: Plant materials represent a significant source in traditional medical practices for treating many disorders. However, many pharmacological studies have provided the basis for their therapeutic potential. Objectives: This work aimed to assess the effects of the methanolic extract of date...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Superior University Lahore, Pakistan
2025-03-01
|
| Series: | International Journal of Pharmacy & Integrated Health Sciences |
| Subjects: | |
| Online Access: | https://ijpihs.pk/index.php/IJPIHS/article/view/218 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1839641599073583104 |
|---|---|
| author | Musab Abdelrahim Elhadi Ahmed Imad Taj-Eldin Abd-Elwahab Mohammed |
| author_facet | Musab Abdelrahim Elhadi Ahmed Imad Taj-Eldin Abd-Elwahab Mohammed |
| author_sort | Musab Abdelrahim |
| collection | DOAJ |
| description |
Background: Plant materials represent a significant source in traditional medical practices for treating many disorders. However, many pharmacological studies have provided the basis for their therapeutic potential. Objectives: This work aimed to assess the effects of the methanolic extract of date palm pollen on some fertility parameters in rats. Methodology: Experiments were performed using conventional methods for extraction of plant material (by methanolic maceration) and for fertility testing in rats. Twenty sexually mature rats were tested in the current study (10 males and 10 female rats) for 28 days. The animals were allocated to control and test groups of males and females (5 animals/group). The control groups of males and females were administered with distilled water, whereas the test groups received daily oral doses of the plant extract at 250 mg/kg. Results: The animals were sacrificed at the end of the study to determine the fertility parameters. The results showed that the plant material exhibited an estrogenic property, as evidenced by the significant elevation of estradiol serum levels in both sexes. Moreover, epididymal sperm count showed a significant elevation in the test group of male animals compared to the control group of male animals. Conclusion: These findings could support and validate the ethnomedicinal uses of the plant material in treating some male fertility disorders and could provide a candidate source for drug development.
|
| format | Article |
| id | doaj-art-72793b79c0de481580847d28c36a65e1 |
| institution | Matheson Library |
| issn | 2958-1656 2789-2840 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Superior University Lahore, Pakistan |
| record_format | Article |
| series | International Journal of Pharmacy & Integrated Health Sciences |
| spelling | doaj-art-72793b79c0de481580847d28c36a65e12025-07-03T07:00:07ZengSuperior University Lahore, PakistanInternational Journal of Pharmacy & Integrated Health Sciences2958-16562789-28402025-03-016110.56536/ijpihs.v6i1.218EFFECTS OF DATE PALM POLLEN EXTRACT (PHOENIX DACTYLIFERA L.) ON REPRODUCTIVE FUNCTION IN RATSMusab Abdelrahim0Elhadi Ahmed1Imad Taj-Eldin2Abd-Elwahab Mohammed3Department of Pharmacology, Faculty of Pharmacy, University of Sinnar, Sudan.Department of Pharmacognosy, Faculty of Pharmacy, University of Gezira, SudanDepartment of Pharmacology, Faculty of Pharmacy, University of Gezira, SudanDepartment of Pharmacology, Faculty of Pharmacy, National Ribat University, Sudan Background: Plant materials represent a significant source in traditional medical practices for treating many disorders. However, many pharmacological studies have provided the basis for their therapeutic potential. Objectives: This work aimed to assess the effects of the methanolic extract of date palm pollen on some fertility parameters in rats. Methodology: Experiments were performed using conventional methods for extraction of plant material (by methanolic maceration) and for fertility testing in rats. Twenty sexually mature rats were tested in the current study (10 males and 10 female rats) for 28 days. The animals were allocated to control and test groups of males and females (5 animals/group). The control groups of males and females were administered with distilled water, whereas the test groups received daily oral doses of the plant extract at 250 mg/kg. Results: The animals were sacrificed at the end of the study to determine the fertility parameters. The results showed that the plant material exhibited an estrogenic property, as evidenced by the significant elevation of estradiol serum levels in both sexes. Moreover, epididymal sperm count showed a significant elevation in the test group of male animals compared to the control group of male animals. Conclusion: These findings could support and validate the ethnomedicinal uses of the plant material in treating some male fertility disorders and could provide a candidate source for drug development. https://ijpihs.pk/index.php/IJPIHS/article/view/218FertilityPhoenix dactyliferaSperm characteristicsTraditional medicine |
| spellingShingle | Musab Abdelrahim Elhadi Ahmed Imad Taj-Eldin Abd-Elwahab Mohammed EFFECTS OF DATE PALM POLLEN EXTRACT (PHOENIX DACTYLIFERA L.) ON REPRODUCTIVE FUNCTION IN RATS International Journal of Pharmacy & Integrated Health Sciences Fertility Phoenix dactylifera Sperm characteristics Traditional medicine |
| title | EFFECTS OF DATE PALM POLLEN EXTRACT (PHOENIX DACTYLIFERA L.) ON REPRODUCTIVE FUNCTION IN RATS |
| title_full | EFFECTS OF DATE PALM POLLEN EXTRACT (PHOENIX DACTYLIFERA L.) ON REPRODUCTIVE FUNCTION IN RATS |
| title_fullStr | EFFECTS OF DATE PALM POLLEN EXTRACT (PHOENIX DACTYLIFERA L.) ON REPRODUCTIVE FUNCTION IN RATS |
| title_full_unstemmed | EFFECTS OF DATE PALM POLLEN EXTRACT (PHOENIX DACTYLIFERA L.) ON REPRODUCTIVE FUNCTION IN RATS |
| title_short | EFFECTS OF DATE PALM POLLEN EXTRACT (PHOENIX DACTYLIFERA L.) ON REPRODUCTIVE FUNCTION IN RATS |
| title_sort | effects of date palm pollen extract phoenix dactylifera l on reproductive function in rats |
| topic | Fertility Phoenix dactylifera Sperm characteristics Traditional medicine |
| url | https://ijpihs.pk/index.php/IJPIHS/article/view/218 |
| work_keys_str_mv | AT musababdelrahim effectsofdatepalmpollenextractphoenixdactyliferalonreproductivefunctioninrats AT elhadiahmed effectsofdatepalmpollenextractphoenixdactyliferalonreproductivefunctioninrats AT imadtajeldin effectsofdatepalmpollenextractphoenixdactyliferalonreproductivefunctioninrats AT abdelwahabmohammed effectsofdatepalmpollenextractphoenixdactyliferalonreproductivefunctioninrats |