The role of donor-specifi c anti-HLA antibodies in the development of humoral rejection

The role of donor-specifi c anti-HLA antibodies in the development of humoral rejection

Humoral rejection belongs to severe complications of the post-transplant period. Mechanisms of humoral rejection proceed through antibody formation. Donor specific anti-HLA antibodies (anti-HLA DSAs) damage transplant tissues by activating the complement system, leading to the dysfunction and loss o...

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Bibliographic Details
Main Authors: L. K. Tkhatl', I. A. Pashkova, E. D. Kosmacheva
Format: Article
Language:English
Published: N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department 2018-06-01
Series:Трансплантология (Москва)
Subjects:
transplantation of heart
humoral rejection
donor specific anti-hla antibodies
Online Access:https://www.jtransplantologiya.ru/jour/article/view/226
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