Modulating cellular deformability via 3D dextran hydrogel cultivation to regulate the microcirculation of mesenchymal stem cells in murine spleen and liver

For mesenchymal stem cell (MSC) therapy to be effective, the vascular system may be used to deliver and steer the cells to the target tissue. However, the expanded MSCs in petri dishes typically exhibit limited deformability and commonly excluded by the capillary networks when homing to the downstre...

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Bibliographic Details
Main Authors: Xiaolu Zhu, Zheng Wang, Yuanping Shi, Shuang Yao, Fengliang He, Xiuli Cong, Fang Teng
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Experimental and Molecular Pathology
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Online Access:http://www.sciencedirect.com/science/article/pii/S0014480025000371
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