DYNAMICS OF CD34/CD45 POSITIVE CELLS CONCENTRATION IN PERIPHERAL BLOOD OF PATIENTS AFTER ORTHOTOPIC LIVER TRANSPLANTATION AND PARTIAL LIVER RESECTION

Number of CD34/CD45+ cells were determined in blood of pediatric recipients and adult living-related liver do- nors. It has been investigated 15 pairs of recipients (aged from 4 to 60 months) and donors (29 ± 5 years). All the children had liver cirrhosis caused by congenital and inherited diseases...

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Main Authors: O. P. Shevchenko, O. M. Tsirulnikova, R. M. Kurabekova, S. A. Lugovskaya, E. V. Naumova, N. Sh. Muratova, I. E. Tsirulnikova, S. V. Gautier
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2011-06-01
Series:Вестник трансплантологии и искусственных органов
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Online Access:https://journal.transpl.ru/vtio/article/view/409
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Summary:Number of CD34/CD45+ cells were determined in blood of pediatric recipients and adult living-related liver do- nors. It has been investigated 15 pairs of recipients (aged from 4 to 60 months) and donors (29 ± 5 years). All the children had liver cirrhosis caused by congenital and inherited diseases of hepatobiliary system. Concentration of CD34/CD45+ cells in venous blood of recipients was higher than in donors. In recipients level of CD34/CD45+ cells did not correlate with sex, age, weight and height but did correlate with some biochemical parameters related to liver function. After liver transplantation number of CD34/CD45+ cells did not change in peripheral blood of recipients. In donors partial liver resection did not cause statistically significant changes in number or concentration of CD34/CD45+ cells in blood. Presented data suggests that neither liver transplantation nor liver resection has remarkable influence on number of CD34/CD45 + cells in peripheral blood.
ISSN:1995-1191