Personalized medicine in gynecology and obstetrics: new diagnostic and therapeutic strategies

This journal issue presents studies in the field of obstetrics, gynecology and reproductive medicine. The original articles consider the genetic aspects of preeclampsia, including the role of NOS3 gene rs1799983 polymorphism, modern approaches for predicting uterine fibroids using neural network tec...

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Main Authors: A. D. Makatsariya, A. V. Vorobev
Format: Article
Language:Russian
Published: IRBIS LLC 2025-05-01
Series:Акушерство, гинекология и репродукция
Subjects:
Online Access:https://www.gynecology.su/jour/article/view/2424
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author A. D. Makatsariya
A. V. Vorobev
author_facet A. D. Makatsariya
A. V. Vorobev
author_sort A. D. Makatsariya
collection DOAJ
description This journal issue presents studies in the field of obstetrics, gynecology and reproductive medicine. The original articles consider the genetic aspects of preeclampsia, including the role of NOS3 gene rs1799983 polymorphism, modern approaches for predicting uterine fibroids using neural network technologies, and vasopressin value as a marker of premature birth. Particular attention is paid to personalized methods of treating coagulopathic bleeding based on thromboelastometry and pregnancy management in chronic kidney pathology. The review articles analyze the pharmacological properties of iron fumarate, the role of the ARID1A gene in gynecological oncology, microbiome impact on the effectiveness of assisted reproductive technologies and the pathogenesis of fetal inflammatory syndrome. Clinical observation describes a rare case of spontaneous uterine rupture, and a historical analysis of forgotten obstetric techniques is presented.
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institution Matheson Library
issn 2313-7347
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publishDate 2025-05-01
publisher IRBIS LLC
record_format Article
series Акушерство, гинекология и репродукция
spelling doaj-art-6faf9a3b8dbf4db0bd768d0b19e07b132025-08-03T19:55:19ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942025-05-0119215215710.17749/2313-7347/ob.gyn.rep.2025.637964Personalized medicine in gynecology and obstetrics: new diagnostic and therapeutic strategiesA. D. Makatsariya0A. V. Vorobev1Sechenov UniversitySechenov UniversityThis journal issue presents studies in the field of obstetrics, gynecology and reproductive medicine. The original articles consider the genetic aspects of preeclampsia, including the role of NOS3 gene rs1799983 polymorphism, modern approaches for predicting uterine fibroids using neural network technologies, and vasopressin value as a marker of premature birth. Particular attention is paid to personalized methods of treating coagulopathic bleeding based on thromboelastometry and pregnancy management in chronic kidney pathology. The review articles analyze the pharmacological properties of iron fumarate, the role of the ARID1A gene in gynecological oncology, microbiome impact on the effectiveness of assisted reproductive technologies and the pathogenesis of fetal inflammatory syndrome. Clinical observation describes a rare case of spontaneous uterine rupture, and a historical analysis of forgotten obstetric techniques is presented.https://www.gynecology.su/jour/article/view/2424preeclampsianos3 gene polymorphismvenous thrombosisuterine fibroidsneural network analysispremature birthvasopressinchronic kidney diseasecoagulopathic bleedingthromboelastometryferrous fumaratemicrobiomeassisted reproductive technologiesarid1a genefetal inflammatory syndromeuterine rupture
spellingShingle A. D. Makatsariya
A. V. Vorobev
Personalized medicine in gynecology and obstetrics: new diagnostic and therapeutic strategies
Акушерство, гинекология и репродукция
preeclampsia
nos3 gene polymorphism
venous thrombosis
uterine fibroids
neural network analysis
premature birth
vasopressin
chronic kidney disease
coagulopathic bleeding
thromboelastometry
ferrous fumarate
microbiome
assisted reproductive technologies
arid1a gene
fetal inflammatory syndrome
uterine rupture
title Personalized medicine in gynecology and obstetrics: new diagnostic and therapeutic strategies
title_full Personalized medicine in gynecology and obstetrics: new diagnostic and therapeutic strategies
title_fullStr Personalized medicine in gynecology and obstetrics: new diagnostic and therapeutic strategies
title_full_unstemmed Personalized medicine in gynecology and obstetrics: new diagnostic and therapeutic strategies
title_short Personalized medicine in gynecology and obstetrics: new diagnostic and therapeutic strategies
title_sort personalized medicine in gynecology and obstetrics new diagnostic and therapeutic strategies
topic preeclampsia
nos3 gene polymorphism
venous thrombosis
uterine fibroids
neural network analysis
premature birth
vasopressin
chronic kidney disease
coagulopathic bleeding
thromboelastometry
ferrous fumarate
microbiome
assisted reproductive technologies
arid1a gene
fetal inflammatory syndrome
uterine rupture
url https://www.gynecology.su/jour/article/view/2424
work_keys_str_mv AT admakatsariya personalizedmedicineingynecologyandobstetricsnewdiagnosticandtherapeuticstrategies
AT avvorobev personalizedmedicineingynecologyandobstetricsnewdiagnosticandtherapeuticstrategies