Influence of hypothyroidism on renal function of lithium-treated patients
Roberto Lozano, Reyes Marín, María-Jesús Santacruz Pharmacy Department, Aragones Health Service, Zaragoza, SpainSeveral studies have shown that lithium maintenance treatment for bipolar disorder (BD) is associated with chronic kidney disease (CKD).1&...
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Dove Medical Press
2015-12-01
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Series: | Neuropsychiatric Disease and Treatment |
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author | Lozano R Marín R Santacruz M |
author_facet | Lozano R Marín R Santacruz M |
author_sort | Lozano R |
collection | DOAJ |
description | Roberto Lozano, Reyes Marín, María-Jesús Santacruz Pharmacy Department, Aragones Health Service, Zaragoza, SpainSeveral studies have shown that lithium maintenance treatment for bipolar disorder (BD) is associated with chronic kidney disease (CKD).1–3 Three recent and large controlled studies concluded that lithium treatment, within recommended serum levels, may increase the risk of induced end-stage renal disease by twofold1,2 or, alternatively, CKD is associated with BD independent of drug treatment.3 Moreover, review of the safety data on lithium shows a 0–5 mL/min reduction in glomerular filtration rate and a clear reduction in urinary concentrating capacity, during an observation period of 1 year.4 |
format | Article |
id | doaj-art-6f6f3fff4d444c1abd08663dec811a98 |
institution | Matheson Library |
issn | 1178-2021 |
language | English |
publishDate | 2015-12-01 |
publisher | Dove Medical Press |
record_format | Article |
series | Neuropsychiatric Disease and Treatment |
spelling | doaj-art-6f6f3fff4d444c1abd08663dec811a982025-06-26T01:58:34ZengDove Medical PressNeuropsychiatric Disease and Treatment1178-20212015-12-01Volume 12Issue 1252725089Influence of hypothyroidism on renal function of lithium-treated patientsLozano R0Marín RSantacruz MPharmacyRoberto Lozano, Reyes Marín, María-Jesús Santacruz Pharmacy Department, Aragones Health Service, Zaragoza, SpainSeveral studies have shown that lithium maintenance treatment for bipolar disorder (BD) is associated with chronic kidney disease (CKD).1–3 Three recent and large controlled studies concluded that lithium treatment, within recommended serum levels, may increase the risk of induced end-stage renal disease by twofold1,2 or, alternatively, CKD is associated with BD independent of drug treatment.3 Moreover, review of the safety data on lithium shows a 0–5 mL/min reduction in glomerular filtration rate and a clear reduction in urinary concentrating capacity, during an observation period of 1 year.4https://www.dovepress.com/influence-of-hypothyroidism-on-renal-functionnbspof-lithium-treated-pa-peer-reviewed-fulltext-article-NDTLithiumhypothyroidismkidney |
spellingShingle | Lozano R Marín R Santacruz M Influence of hypothyroidism on renal function of lithium-treated patients Neuropsychiatric Disease and Treatment Lithium hypothyroidism kidney |
title | Influence of hypothyroidism on renal function of lithium-treated patients |
title_full | Influence of hypothyroidism on renal function of lithium-treated patients |
title_fullStr | Influence of hypothyroidism on renal function of lithium-treated patients |
title_full_unstemmed | Influence of hypothyroidism on renal function of lithium-treated patients |
title_short | Influence of hypothyroidism on renal function of lithium-treated patients |
title_sort | influence of hypothyroidism on renal function amp nbsp of lithium treated patients |
topic | Lithium hypothyroidism kidney |
url | https://www.dovepress.com/influence-of-hypothyroidism-on-renal-functionnbspof-lithium-treated-pa-peer-reviewed-fulltext-article-NDT |
work_keys_str_mv | AT lozanor influenceofhypothyroidismonrenalfunctionampnbspoflithiumtreatedpatients AT marinr influenceofhypothyroidismonrenalfunctionampnbspoflithiumtreatedpatients AT santacruzm influenceofhypothyroidismonrenalfunctionampnbspoflithiumtreatedpatients |