Influence of hypothyroidism on renal function of lithium-treated patients

Roberto Lozano, Reyes Marín, María-Jesús Santacruz Pharmacy Department, Aragones Health Service, Zaragoza, SpainSeveral studies have shown that lithium maintenance treatment for bipolar disorder (BD) is associated with chronic kidney disease (CKD).1&...

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Main Authors: Lozano R, Marín R, Santacruz M
Format: Article
Language:English
Published: Dove Medical Press 2015-12-01
Series:Neuropsychiatric Disease and Treatment
Subjects:
Online Access:https://www.dovepress.com/influence-of-hypothyroidism-on-renal-functionnbspof-lithium-treated-pa-peer-reviewed-fulltext-article-NDT
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author Lozano R
Marín R
Santacruz M
author_facet Lozano R
Marín R
Santacruz M
author_sort Lozano R
collection DOAJ
description Roberto Lozano, Reyes Marín, María-Jesús Santacruz Pharmacy Department, Aragones Health Service, Zaragoza, SpainSeveral studies have shown that lithium maintenance treatment for bipolar disorder (BD) is associated with chronic kidney disease (CKD).1–3 Three recent and large controlled studies concluded that lithium treatment, within recommended serum levels, may increase the risk of induced end-stage renal disease by twofold1,2 or, alternatively, CKD is associated with BD independent of drug treatment.3 Moreover, review of the safety data on lithium shows a 0–5 mL/min reduction in glomerular filtration rate and a clear reduction in urinary concentrating capacity, during an observation period of 1 year.4
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spelling doaj-art-6f6f3fff4d444c1abd08663dec811a982025-06-26T01:58:34ZengDove Medical PressNeuropsychiatric Disease and Treatment1178-20212015-12-01Volume 12Issue 1252725089Influence of hypothyroidism on renal function of lithium-treated patientsLozano R0Marín RSantacruz MPharmacyRoberto Lozano, Reyes Marín, María-Jesús Santacruz Pharmacy Department, Aragones Health Service, Zaragoza, SpainSeveral studies have shown that lithium maintenance treatment for bipolar disorder (BD) is associated with chronic kidney disease (CKD).1–3 Three recent and large controlled studies concluded that lithium treatment, within recommended serum levels, may increase the risk of induced end-stage renal disease by twofold1,2 or, alternatively, CKD is associated with BD independent of drug treatment.3 Moreover, review of the safety data on lithium shows a 0–5 mL/min reduction in glomerular filtration rate and a clear reduction in urinary concentrating capacity, during an observation period of 1 year.4https://www.dovepress.com/influence-of-hypothyroidism-on-renal-functionnbspof-lithium-treated-pa-peer-reviewed-fulltext-article-NDTLithiumhypothyroidismkidney
spellingShingle Lozano R
Marín R
Santacruz M
Influence of hypothyroidism on renal function of lithium-treated patients
Neuropsychiatric Disease and Treatment
Lithium
hypothyroidism
kidney
title Influence of hypothyroidism on renal function of lithium-treated patients
title_full Influence of hypothyroidism on renal function of lithium-treated patients
title_fullStr Influence of hypothyroidism on renal function of lithium-treated patients
title_full_unstemmed Influence of hypothyroidism on renal function of lithium-treated patients
title_short Influence of hypothyroidism on renal function of lithium-treated patients
title_sort influence of hypothyroidism on renal function amp nbsp of lithium treated patients
topic Lithium
hypothyroidism
kidney
url https://www.dovepress.com/influence-of-hypothyroidism-on-renal-functionnbspof-lithium-treated-pa-peer-reviewed-fulltext-article-NDT
work_keys_str_mv AT lozanor influenceofhypothyroidismonrenalfunctionampnbspoflithiumtreatedpatients
AT marinr influenceofhypothyroidismonrenalfunctionampnbspoflithiumtreatedpatients
AT santacruzm influenceofhypothyroidismonrenalfunctionampnbspoflithiumtreatedpatients