The Effects of the Association Between a High-Fat Diet and Physical Exercise on BDNF Expression in the Hippocampus: A Comprehensive Review

High-fat diets, characterised by their high lipid content, have been associated with structural and functional alterations in the hippocampus of rodents, including a reduction in the expression of brain-derived neurotrophic factor (BDNF), which negatively impacts learning and memory. Evidence sugges...

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Main Authors: Francisca Tayná da Silva Gomes, Antônio Vicente Dias de Andrade, Paloma Katlheen Moura Melo, Roque Ribeiro da Silva Júnior, Débora Lopes Silva de Souza, Élyssa Adriolly Freitas Tavares, Ingrid Garcia de Sena, Thales Allyrio Araújo de Medeiros Fernandes, Paulo Leonardo Araújo de Góis Morais, Ivana Alice Teixeira Fonseca, Cibele dos Santos Borges, José Rodolfo Lopes de Paiva Cavalcanti
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Life
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Online Access:https://www.mdpi.com/2075-1729/15/6/945
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