GLUCOSE EXCHANGE DISORDERS IN PATIENTS TAKING GLUCOCORTICOSTEROIDS: FEATURES OF CLINICAL MANIFESTATIONS AND CORRECTION

The review deals with the problem of carbohydrate metabolism disorders in patients undergoing corticosteroid therapy, relevant for specialists in various fields. The article describes the epidemiology and risk factors for the development of carbohydrate metabolism disorders when using glucocorticost...

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Main Authors: Al’bert Yu. Selimov, Lyudmila N. Eliseeva, Valeriya P. Kurinnaya, Sergei P. Oranskii
Format: Article
Language:Russian
Published: Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” 2019-03-01
Series:Кубанский научный медицинский вестник
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Online Access:https://ksma.elpub.ru/jour/article/view/1626
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author Al’bert Yu. Selimov
Lyudmila N. Eliseeva
Valeriya P. Kurinnaya
Sergei P. Oranskii
author_facet Al’bert Yu. Selimov
Lyudmila N. Eliseeva
Valeriya P. Kurinnaya
Sergei P. Oranskii
author_sort Al’bert Yu. Selimov
collection DOAJ
description The review deals with the problem of carbohydrate metabolism disorders in patients undergoing corticosteroid therapy, relevant for specialists in various fields. The article describes the epidemiology and risk factors for the development of carbohydrate metabolism disorders when using glucocorticosteroids. Contemporary information is provided about the diagnostics, prevalence and pathogenesis of steroid-induced hyperglycemia. A particular attention is paid to current data on various disorders of carbohydrate metabolism in patients with a therapeutic profile. Main approaches to the correction of glycemia in the steroid-induced disorders of carbohydrate metabolism using modern therapy are considered elucidated.Conclusion. The widespread use of glucocorticosteroids, significant prevalence of the steroid-induced disorders of carbohydrate metabolism, features of the pathogenetic mechanisms of steroid-induced diabetes mellitus determine the need to create algorithms for the diagnosis and treatment of these conditions. A conclusion is made that rational glucose-lowering therapy that takes into account the pathogenetic and clinical aspects of the steroid-induced disorders of carbohydrate metabolism, can reduce the rate of macro- and microvascular complications.Conflict of interest: the authors declare no conflict of interest.
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institution Matheson Library
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language Russian
publishDate 2019-03-01
publisher Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”
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spelling doaj-art-6e3b3f2bdbb542f7b45a78971d4bae1f2025-08-04T13:05:13ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442019-03-0126120921810.25207/1608-6228-2019-26-1-209-2181079GLUCOSE EXCHANGE DISORDERS IN PATIENTS TAKING GLUCOCORTICOSTEROIDS: FEATURES OF CLINICAL MANIFESTATIONS AND CORRECTIONAl’bert Yu. Selimov0Lyudmila N. Eliseeva1Valeriya P. Kurinnaya2Sergei P. Oranskii3Kuban State Medical University, Ministry of Healthcare of the Russian FederationKuban State Medical University, Ministry of Healthcare of the Russian FederationResearch Institute — Regional Clinical Hospital No. 1 n.a. prof. S. V. Ochapovsky, Ministry of Health of the Krasnodar KraiKuban State Medical University, Ministry of Healthcare of the Russian FederationThe review deals with the problem of carbohydrate metabolism disorders in patients undergoing corticosteroid therapy, relevant for specialists in various fields. The article describes the epidemiology and risk factors for the development of carbohydrate metabolism disorders when using glucocorticosteroids. Contemporary information is provided about the diagnostics, prevalence and pathogenesis of steroid-induced hyperglycemia. A particular attention is paid to current data on various disorders of carbohydrate metabolism in patients with a therapeutic profile. Main approaches to the correction of glycemia in the steroid-induced disorders of carbohydrate metabolism using modern therapy are considered elucidated.Conclusion. The widespread use of glucocorticosteroids, significant prevalence of the steroid-induced disorders of carbohydrate metabolism, features of the pathogenetic mechanisms of steroid-induced diabetes mellitus determine the need to create algorithms for the diagnosis and treatment of these conditions. A conclusion is made that rational glucose-lowering therapy that takes into account the pathogenetic and clinical aspects of the steroid-induced disorders of carbohydrate metabolism, can reduce the rate of macro- and microvascular complications.Conflict of interest: the authors declare no conflict of interest.https://ksma.elpub.ru/jour/article/view/1626glucocorticosteroidssteroid-induced diabetes mellituscarbohydrate metabolism disorders
spellingShingle Al’bert Yu. Selimov
Lyudmila N. Eliseeva
Valeriya P. Kurinnaya
Sergei P. Oranskii
GLUCOSE EXCHANGE DISORDERS IN PATIENTS TAKING GLUCOCORTICOSTEROIDS: FEATURES OF CLINICAL MANIFESTATIONS AND CORRECTION
Кубанский научный медицинский вестник
glucocorticosteroids
steroid-induced diabetes mellitus
carbohydrate metabolism disorders
title GLUCOSE EXCHANGE DISORDERS IN PATIENTS TAKING GLUCOCORTICOSTEROIDS: FEATURES OF CLINICAL MANIFESTATIONS AND CORRECTION
title_full GLUCOSE EXCHANGE DISORDERS IN PATIENTS TAKING GLUCOCORTICOSTEROIDS: FEATURES OF CLINICAL MANIFESTATIONS AND CORRECTION
title_fullStr GLUCOSE EXCHANGE DISORDERS IN PATIENTS TAKING GLUCOCORTICOSTEROIDS: FEATURES OF CLINICAL MANIFESTATIONS AND CORRECTION
title_full_unstemmed GLUCOSE EXCHANGE DISORDERS IN PATIENTS TAKING GLUCOCORTICOSTEROIDS: FEATURES OF CLINICAL MANIFESTATIONS AND CORRECTION
title_short GLUCOSE EXCHANGE DISORDERS IN PATIENTS TAKING GLUCOCORTICOSTEROIDS: FEATURES OF CLINICAL MANIFESTATIONS AND CORRECTION
title_sort glucose exchange disorders in patients taking glucocorticosteroids features of clinical manifestations and correction
topic glucocorticosteroids
steroid-induced diabetes mellitus
carbohydrate metabolism disorders
url https://ksma.elpub.ru/jour/article/view/1626
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AT lyudmilaneliseeva glucoseexchangedisordersinpatientstakingglucocorticosteroidsfeaturesofclinicalmanifestationsandcorrection
AT valeriyapkurinnaya glucoseexchangedisordersinpatientstakingglucocorticosteroidsfeaturesofclinicalmanifestationsandcorrection
AT sergeiporanskii glucoseexchangedisordersinpatientstakingglucocorticosteroidsfeaturesofclinicalmanifestationsandcorrection