Present State of in vitro and in vivo Studies on Efficacy of Medical Nonspecific Protective Agents with Respect to Genotype IV Coronavirus Causing Severe Acute Respiratory Syndrome
The results of the in vitro studies on the efficacy of medical nonspecific protective agents from various pharmacological groups showed that some drugs, such as velferon, alferon, betaferon, ribavirin and lopinavir were active against TOPC virus, that permitted to recommend them for estimation of th...
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| Format: | Article |
| Language: | Russian |
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LLC "Publishing House OKI"
2020-05-01
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| Series: | Антибиотики и Химиотерапия |
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| Online Access: | https://www.antibiotics-chemotherapy.ru/jour/article/view/402 |
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| author | V. N. Shchukina S. YA. Loginova S. V. Borisevich V. P. Bonderev |
| author_facet | V. N. Shchukina S. YA. Loginova S. V. Borisevich V. P. Bonderev |
| author_sort | V. N. Shchukina |
| collection | DOAJ |
| description | The results of the in vitro studies on the efficacy of medical nonspecific protective agents from various pharmacological groups showed that some drugs, such as velferon, alferon, betaferon, ribavirin and lopinavir were active against TOPC virus, that permitted to recommend them for estimation of their activity on laboratory animals. The data on the in vivo activity of pharmacological drugs with respect to TOPC virus are rather scanty and it is difficult to predetermine their efficacy. The danger of TOPC virus latent circulation among wild animals in China requires research of new efficient medical agents for protection of the people from the pathogen in the Russian Federation. |
| format | Article |
| id | doaj-art-6d545b51da194f9482f19949395c7caa |
| institution | Matheson Library |
| issn | 0235-2990 |
| language | Russian |
| publishDate | 2020-05-01 |
| publisher | LLC "Publishing House OKI" |
| record_format | Article |
| series | Антибиотики и Химиотерапия |
| spelling | doaj-art-6d545b51da194f9482f19949395c7caa2025-08-03T13:04:43ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-05-01569-104146401Present State of in vitro and in vivo Studies on Efficacy of Medical Nonspecific Protective Agents with Respect to Genotype IV Coronavirus Causing Severe Acute Respiratory SyndromeV. N. Shchukina0S. YA. Loginova1S. V. Borisevich2V. P. Bonderev3Филиал федерального государственного учреждения 48 Центральный научно-исследовательский институт Министерства обороны Российской Федерации - Вирусологический центрФилиал федерального государственного учреждения 48 Центральный научно-исследовательский институт Министерства обороны Российской Федерации - Вирусологический центрФилиал федерального государственного учреждения 48 Центральный научно-исследовательский институт Министерства обороны Российской Федерации - Вирусологический центрФилиал федерального государственного учреждения 48 Центральный научно-исследовательский институт Министерства обороны Российской Федерации - Вирусологический центрThe results of the in vitro studies on the efficacy of medical nonspecific protective agents from various pharmacological groups showed that some drugs, such as velferon, alferon, betaferon, ribavirin and lopinavir were active against TOPC virus, that permitted to recommend them for estimation of their activity on laboratory animals. The data on the in vivo activity of pharmacological drugs with respect to TOPC virus are rather scanty and it is difficult to predetermine their efficacy. The danger of TOPC virus latent circulation among wild animals in China requires research of new efficient medical agents for protection of the people from the pathogen in the Russian Federation.https://www.antibiotics-chemotherapy.ru/jour/article/view/402evere acute respiratory syndrome virusinterferoninterferon inductorsantiviral efficacychemotherapy |
| spellingShingle | V. N. Shchukina S. YA. Loginova S. V. Borisevich V. P. Bonderev Present State of in vitro and in vivo Studies on Efficacy of Medical Nonspecific Protective Agents with Respect to Genotype IV Coronavirus Causing Severe Acute Respiratory Syndrome Антибиотики и Химиотерапия evere acute respiratory syndrome virus interferon interferon inductors antiviral efficacy chemotherapy |
| title | Present State of in vitro and in vivo Studies on Efficacy of Medical Nonspecific Protective Agents with Respect to Genotype IV Coronavirus Causing Severe Acute Respiratory Syndrome |
| title_full | Present State of in vitro and in vivo Studies on Efficacy of Medical Nonspecific Protective Agents with Respect to Genotype IV Coronavirus Causing Severe Acute Respiratory Syndrome |
| title_fullStr | Present State of in vitro and in vivo Studies on Efficacy of Medical Nonspecific Protective Agents with Respect to Genotype IV Coronavirus Causing Severe Acute Respiratory Syndrome |
| title_full_unstemmed | Present State of in vitro and in vivo Studies on Efficacy of Medical Nonspecific Protective Agents with Respect to Genotype IV Coronavirus Causing Severe Acute Respiratory Syndrome |
| title_short | Present State of in vitro and in vivo Studies on Efficacy of Medical Nonspecific Protective Agents with Respect to Genotype IV Coronavirus Causing Severe Acute Respiratory Syndrome |
| title_sort | present state of in vitro and in vivo studies on efficacy of medical nonspecific protective agents with respect to genotype iv coronavirus causing severe acute respiratory syndrome |
| topic | evere acute respiratory syndrome virus interferon interferon inductors antiviral efficacy chemotherapy |
| url | https://www.antibiotics-chemotherapy.ru/jour/article/view/402 |
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