A Technology for Forming Tablet Cores of Complex Geometric Shapes for Further Coating, with a Multivitamin Product as a Case Study

A Technology for Forming Tablet Cores of Complex Geometric Shapes for Further Coating, with a Multivitamin Product as a Case Study

INRODUCTION. The traditional technology of layering components onto sugar gra­nules to produce medicinal products in the form of dragees has a number of disadvantages, including labour intensity, as well as the exposure of intermediates to liquids and high temperatures at certain production stages,...

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Bibliographic Details
Main Authors: V. V. Kosenko, A. V. Bolotova, A. S. Gavrilov, N. D. Bunyatyan, V. A. Evteev, A. M. Shevchenko, A. B. Prokofiev
Format: Article
Language:Russian
Published: Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) 2025-05-01
Series:Регуляторные исследования и экспертиза лекарственных средств
Subjects:
tablets
dragees
vitamins
resistance to crushing
direct compression
spherical tablet cores
pilot industrial production
pharmaceutical production
production technologies
dragee production
Online Access:https://www.vedomostincesmp.ru/jour/article/view/727
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