LIMITATIONS OF HUMAN LEUKOCYTE ANTIGEN MOLECULAR TYPING METHODS FOR PATIENTS WITH ACUTE MYELOID LEUKEMIA RELAPSE AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION
Aim. The work purposed to compare molecular typing methods with different resolutions in clinical cases without loss of heterozygosity (LOH) in HLA genes. Methods. HLA typing was performed using molecular techniques based on sequence-specific primers (SSP) or high-resolution sequencing (NGS and S...
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Main Authors: | L.O. Sishchuk, I.I. Tubaltseva, N.A. Tsokolenko, A.O. Maksymchuk, A. V. Kukhol, V.V. Andrusenko, A.O. Mazanova, Y.A. Hrohul |
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Format: | Article |
Language: | English |
Published: |
National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2025-04-01
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Series: | Biotechnologia Acta |
Subjects: | |
Online Access: | https://biotechnology.kiev.ua/images/BTA/2025/2_2025/Sishchuk2_2025%20.pdf |
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