Changing of cytokine status in acute period of tick-borne neuroinfections in children
Activity of cytokines of tick-borne infection of children was researched. Revealed low level of interferon-γ concentration testify about abnormality of cellular link immune protection and typical for focal forms of tick-borne encephalitis. Severe forms of disease run with background increase of inte...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Siberian State Medical University (Tomsk)
2009-02-01
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Series: | Бюллетень сибирской медицины |
Subjects: | |
Online Access: | https://bulletin.ssmu.ru/jour/article/view/1755 |
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Summary: | Activity of cytokines of tick-borne infection of children was researched. Revealed low level of interferon-γ concentration testify about abnormality of cellular link immune protection and typical for focal forms of tick-borne encephalitis. Severe forms of disease run with background increase of interleukin-6 and interleukin10. Maximum increase of tumor necrosis factor-α was detected in cases of mixed-infections. Borreliosis infection flows with background domination of Th-2 over Th-1 type of immune response. |
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ISSN: | 1682-0363 1819-3684 |